Results 41 to 50 of about 6,074,585 (308)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Immunological and microbiological aspects of atopic dermatitis. A review

Consilium Medicum
Atopic dermatitis (AtD) is a common chronic skin disease. Its prevalence has been increasing over the past few decades, reaching 20% in children and 10% in adults. AtD can occur at any age, although 45% of all cases begin within first six months of life,
Julia A. Kandrashlina, Ekaterina A. Orlova, Oksana A. Kulieva   +2 more
doaj   +1 more source

Changes in goslings’ blood pattern under the influence of different doses additives of selenium in forages

Науковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Гжицького. Серія: Сільськогосподарські науки, 2020
According to many scientists, the list of trace elements that are currently used in compound feeds for various types of poultry is clearly insufficient. In recent years, applied research has been conducted to determine the physiological needs of poultry ...
S. V. Sobolieva, B. V. Gutyj, O. I. Sobolev   +2 more
doaj   +1 more source

Frosting Weights for Better Continual Training [PDF]

2019 18th IEEE International Conference On Machine Learning And Applications (ICMLA), 2019
Training a neural network model can be a lifelong learning process and is a computationally intensive one. A severe adverse effect that may occur in deep neural network models is that they can suffer from catastrophic forgetting during retraining on new data.
Xiaofeng Zhu 0004, Feng Liu, Goce Trajcevski, Dingding Wang 0001   +3 more
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Evaluating Continuous Training Programs Using the Generalized Propensity Score [PDF]

This paper assesses the dynamics of treatment effects arising from variation in the duration of training. We use German administrative data that have the extraordinary feature that the amount of treatment varies continuously from 10 days to 395 days (i.e.
Jochen Kluve, Arne Uhlendorff, Hilmar Schneider, Zhong Zhao   +3 more
core   +2 more sources

PROINFLAMMATORY CYTOKINES, LACTOFERRIN, AND Α2-MACROGLOBULIN IN FOLLIC-ULAR FLUID AND SERUM OF WOMEN WITH UTERINE INFERTILITY AT THE START OF IN VITRO FERTILIZATION PROGRAM

Фундаментальная и клиническая медицина, 2017
Aim. To investigate the levels of proinflammatory cytokines [tumor necrosis factor (TNF)-α, interleukin (IL)-6, IL-8, interferon (IFN)-γ), lactoferrin (LF), and α2-macroglobulin (α2-MG) in serum and follicular fluid of women with uterine ...
VICTORIA N. Likhacheva, LYUDMILA V. Renge, LYUDMILA G. Bazhenova, YАNA N. Tretyakova, SVETLANA V. Arkhipova, RAISA M. Zorina   +5 more
doaj  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source