Results 101 to 110 of about 89,082 (299)

Cortical bone continuum damage mechanics constitutive model with stress triaxiality criterion to predict fracture initiation and pattern. [PDF]

Front Bioeng Biotechnol, 2022
Cronin DS, Watson B, Khor F, Gierczycka D, Malcolm S.   +4 more
europepmc   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

Длительная прочность регулирующего клапана шиберного типа с учетом неоднородного распределения температуры [PDF]

, 2012
Для учета неоднородного распределения температуры предложено посредством функций Аррениуса расширить классическую модель механики разрушения Качанова-Работнова-Хейхерста. Предложена неизотермическая теория ползучести с учетом повреждаемости была встроена
Лысенко, Сергей Викторович, Львов, Геннадий Иванович, Перин, Р. П.   +2 more
core  

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Fatigue Damage Estimation through Continuum Damage Mechanics

Procedia Engineering, 2017
Abstract The paper presents an experimental investigation of the fatigue damage behavior of AISI 1020 steel using plasticity coupled continuum damage mechanics (CDM) model. The Model is based on the thermodynamics, a continuum damage variable, D and on the effective stress concept.
Gautam, Abhinav, Ajit, K.P., Sarkar, P.K.   +2 more
openaire   +1 more source

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source

Modeling of damage evaluation in thin composite plate loaded by pressure loading

Applied and Computational Mechanics, 2012
This article presents the results of numerical analysis of elastic damage of thin laminated long fiber-reinforced composite plate consisting of unidirectional layers which is loaded by uniformly distributed pressure.
Dudinský M., Žmindák M., Frnka P.
doaj  

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Plasto-damage modelling for semi-brittle geomaterials

E3S Web of Conferences, 2016
This paper presents an elastoplastic damage model for constitutive modelling of semi-brittle geomaterials showing two irreversible mechanisms. On one hand, the model deals with the plastic behaviour of a porous medium by a new variant of Barcelona Basic ...
Alizadeh Ali, Gatmiri Behrouz
doaj   +1 more source

Formulation of continuous/discontinuous Galerkin methods for strain gradient-dependent damage [PDF]

, 2006
Continuum damage models are widely used to represent the development of microscopic defects that coalesce into a macroscopic crack. The microscopic defects cause a progressive weakening or softening of the material (damage).
Garikipati, K, Molari, L, Wells, GN
core