Results 91 to 100 of about 89,082 (299)

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang   +22 more
wiley   +1 more source

Application of continuum damage mechanics for prediction of wear in tillage tools

open access: yesSmart Agricultural Technology
Wear of tillage tools by hard soil particles is a serious concern in the industry since wear is the primary factor that defines an engaging tool's lifespan, stability, and reliability. Many studies have primarily focused on experimental methods to better
Sahar Ghatrehsamani   +3 more
doaj   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett   +8 more
wiley   +1 more source

Application of a Microstructure-Based ISV Plasticity Damage Model to Study Penetration Mechanics of Metals and Validation through Penetration Study of Aluminum

open access: yesModelling and Simulation in Engineering, 2017
A developed microstructure-based internal state variable (ISV) plasticity damage model is for the first time used for simulating penetration mechanics of aluminum to find out its penetration properties. The ISV damage model tries to explain the interplay
Yangqing Dou   +3 more
doaj   +1 more source

A differential CDM model for fatigue of unidirectional metal matrix composites [PDF]

open access: yes
A multiaxial, isothermal, continuum damage mechanics (CDM) model for fatigue of a unidirectional metal matrix composite volume element is presented. The model is phenomenological, stress based, and assumes a single scalar internal damage variable, the ...
Arnold, S. M., Kruch, S.
core   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

Time dependent reliability model incorporating continuum damage mechanics for high-temperature ceramics [PDF]

open access: yes
Presently there are many opportunities for the application of ceramic materials at elevated temperatures. In the near future ceramic materials are expected to supplant high temperature metal alloys in a number of applications.
Duffy, Stephen F., Gyekenyesi, John P.
core   +1 more source

A finite element strategy coupling a gradient-enhanced damage model and cohesive cracks for quasi-brittle materials [PDF]

open access: yes, 2013
A new combined strategy to describe failure of quasi-brittle materials is presented thus allowing the complete description of the process, from initiation of damage to crack propagation.
Rodríguez Ferran, Antonio   +1 more
core  

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone   +8 more
wiley   +1 more source

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