Results 51 to 60 of about 20,364 (303)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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The J-contour integral in peridynamics via displacements
, 2019 Peridynamics is a nonlocal formulation of solid mechanics capable of unguided modelling of crack initiation, propagation and fracture. Peridynamics is based upon integral equations, thereby avoiding spatial derivatives, which are not defined at ...
Eriksson, Kjell +3 more
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A contour integral method for the Black-Scholes and Heston equations
, 2011 : A contour integral method recently proposed by Weideman [IMA J. Numer. Anal., 30 (2010), pp. 334350] for integrating semidiscrete advection-diffusion PDEs is improved and extended for application to some of the important equations of mathematical ...
in 't Hout, Karel, Weideman, J.A.C.
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Contour integral around a simple pole
, 2016 Complex numbers, complex functions, singularity, analytic function, integrable functions, Cauchy's theoremThe function f(z) = 1/(z – z0) is analytic in the entire z plane, except for a simple pole at z=z0.
Blinder, S
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Closure facilitates contour integration
Vision Research, 2007 Closed contours are often better perceived than those not fully enclosing an area, i.e., open contours. This facilitation of contour integration by closure, however, has been questioned arguing that in earlier studies closed contours were often "smoother" than open ones, because open contours usually had turning points.
Mathes, Birgit, Fahle, Manfred
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
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Determination of view factors by contour integral technique
, 2009 This paper presents the application of contour integral technique to derive the diffuse radiation view factor expressions (analytical) for elements of nuclear reactor fuel bundle.
SRIDHARAN, A, BOPCHE, SB
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Contour integration in the peripheral field
Vision Research, 1999 Contour integration was measured in the normal peripheral field to determine if an explanation based solely on the known peripheral positional uncertainty was sufficient to explain performance. The task involved the detection of paths composed of micropatterns with correlated carrier orientations embedded in a field of similar micropatterns of random ...
Hess, Robert F, Dakin, Steven C
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source