In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Free-Boundary Seepage from Asymmetric Soil Channels
We present an inverse method for the study of the seepage from soil channels without lining. We give integral representations of the complex potential, velocity field, stream lines, free phreatic lines, and contour of the channel by means of Levi-Civitá ...
Adrian Carabineanu
doaj +1 more source
Product integrals II: Contour integrals
AbstractThis paper continues the joint work of the authors begun in the article “On Strong Product Integration” [J. Functional Analysis, submitted]. We consider product integrals along contours; the point of view and development is analogous to the usual complex variable theory of ordinary contour integrals.
Friedman, Charles N, Dollard, John D
openaire +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
On approximate solution of non-elliptic singular integral equation systems in Lebesgue spaces [PDF]
We investigate in this paper problems of theoretical foundation of collocations and mechanical quadratures methods for approximate solution of singular integral equation systems in the case, when their symbols have on the integration contour a finite set
T. Cibotaru
doaj
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Efficient Parameter Estimation and Implementation of a Contour Integral-Based Eigensolver
We consider an eigensolver for computing eigenvalues in a given domain and the corresponding eigenvectors of large-scale matrix pencils. The Sakurai-Sugiura (SS) method is an eigensolver based on complex moments given by contour integrals of matrix ...
Tetsuya Sakurai +2 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Complex and distributional weights for sieved ultraspherical polynomials
Contour integral and distributional orthogonality of sieved ultraspherical polynomials are established for values of the parameters outside the natural range of orthogonality by positive measures on the real line.
Jairo A. Charris, Felix H. Soriano
doaj +1 more source
Direct Computation of 3-D Stress Intensity Factors of Straight and Curved Planar Cracks with the P-Version Finite Element Method and Contour Integral Method. [PDF]
Zhang J, Xu R, He Y, Yang W.
europepmc +1 more source

