Results 61 to 70 of about 41,472 (242)

On the equivalence between SRS and PCO formulations of superstring perturbation theory

open access: yesJournal of High Energy Physics, 2023
We establish the equivalence between two formulations of superstring perturbation theory, one based on integration over the supermoduli space of super Riemann surfaces (SRS), the other based on integration over the bosonic moduli space with insertions of
Charles Wang, Xi Yin
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Perceptual learning in Williams syndrome: looking beyond averages. [PDF]

open access: yesPLoS ONE, 2012
Williams Syndrome is a genetically determined neurodevelopmental disorder characterized by an uneven cognitive profile and surprisingly large neurobehavioral differences among individuals.
Patricia Gervan   +2 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Evaluation of viewing distance on vision tasks using virtual reality technology for children with intermittent exotropia

open access: yesIndian Journal of Ophthalmology
Purpose: This study sought to investigate dynamic visual acuity (DVA), binocular functions, and perceptual eye position (PEP) measured via a virtual reality (VR) evaluation system in children with intermittent exotropia (IXT) at varying viewing distances.
Shengbei Weng, Mengxiang Guo, Feng Chen
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Euler Sums and Contour Integral Representations [PDF]

open access: yesExperimental Mathematics, 1998
This paper develops an approach to the evaluation of Euler sums involving harmonic numbers either linearly or nonlinearly. We give explicit formul{æ} for certain classes of Euler sums in terms of values of the Riemann zeta function at positive integers. The approach is based on simple contour integral representations and residue computations.
Flajolet, Philippe, Salvy, Bruno
openaire   +3 more sources

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Increased Noise in Cortico-Cortical Integration After Mild TBI Measured With the Equivalent Noise Technique

open access: yesFrontiers in Neurology, 2019
The bulk of deficits accompanying mild traumatic brain injury (mTBI) is understood in terms of cortical integration—mnemonic, attentional, and cognitive disturbances are believed to involve integrative action across brain regions.
Tatiana Ruiz   +4 more
doaj   +1 more source

Right ventricular stroke volume assessed by pulmonary artery pulse contour analysis

open access: yesIntensive Care Medicine Experimental, 2020
Background Stroke volume measurement should provide estimates of acute treatment responses. The current pulse contour method estimates left ventricle stroke volume. Heart-lung interactions change right ventricular stroke volume acutely.
David Berger   +5 more
doaj   +1 more source

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