Endoscopic Suture Ligation and Sclerotherapy for Pharyngolaryngeal Venous Malformation
The Laryngoscope, EarlyView.This study evaluated suture ligation combined with sclerotherapy in 53 patients with pharyngolaryngeal venous malformations. A single procedure achieved complete resolution in 79.25% of cases, with no serious complications or need for prophylactic tracheostomy.
Jiajun Tian +5 more
wiley +1 more source
Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria
Medicinal Research Reviews, EarlyView.ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood +7 more
wiley +1 more source
Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future
Medicinal Research Reviews, EarlyView.ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley +1 more source
Task-shifting through community health workers: factors influencing access and utilization of modern family planning methods in Ziniaré, Burkina Faso. [PDF]
Front Reprod HealthKoinda F +12 more
europepmc +1 more source
Neurourology and Urodynamics, EarlyView.ABSTRACT Background & Aims Neurogenic lower urinary tract dysfunction (NLUTD) can produce bothersome urinary symptoms, impact quality of life, and in some cases, lead to deterioration of upper urinary tract function. Intradetrusor injection of onabotulinumtoxin‐A (BoNT‐A) is approved for NLUTD in patients who have an inadequate response to or ...
Shirley L. Wang +2 more
wiley +1 more source
Targeting Soluble Adenylyl Cyclase for On-Demand Contraception. [PDF]
Physiology (Bethesda)Gardner ER, Kopf GS, Buck J, Levin LR.
europepmc +1 more source
Error Traps in Pediatric Neuromuscular Block
Pediatric Anesthesia, EarlyView.ABSTRACT Background Neuromuscular blocking agents are essential for safe pediatric anesthesia but remain a frequent source of preventable morbidity when misused, inadequately monitored, or incompletely reversed. Children, particularly neonates and infants, are especially vulnerable to residual neuromuscular block due to developmental pharmacological ...
Gabriel Soares de Sousa +5 more
wiley +1 more source
Hormonal Contraception and Vestibular Disorders: A Narrative Review of Clinical Implications, Diagnostic Challenges, and Evidence Gaps. [PDF]
CureusCastillo-Bustamante M +2 more
europepmc +1 more source
Hemophilia A: An Ideal Disease for Prenatal Therapy
Prenatal Diagnosis, EarlyView.ABSTRACT Hemophilia A (HA) is the most common inherited coagulation defect. Current state‐of‐the‐art treatment consists of frequent administration of prophylactic infusions of coagulation factor VIII (FVIII) protein or bispecific antibodies that replace the cofactor function of FVIIIa to maintain hemostasis. However, these treatments are far from ideal,
Christopher D. Porada +2 more
wiley +1 more source
Effects of bioinsecticide exposure route on aphids and their natural enemies in oilseed rape
Pest Management Science, EarlyView.Fatty acids, silicone polymers and surfactants reduced aphid numbers but caused natural enemy mortality under direct exposure, while minimal residual activity suggests potential for targeted, compatible use in integrated pest management. Abstract BACKGROUND Myzus persicae Sulzer and Brevicoryne brassicae L.
Aimee J. Tonks +3 more
wiley +1 more source