Results 181 to 190 of about 43,541 (256)

Venous Thromboembolism in Women with Breast and Gynaecological Cancers: What Do We Know and What Should We Do? [PDF]

Clin Appl Thromb Hemost
Poenou G, Corbaux P, Accassat S, Chauleur C, Bertoletti L.   +4 more
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Effectiveness of the etonogestrel subdermal implant in users with overweight and obesity: a systematic literature review. [PDF]

BMJ Sex Reprod Health
Goto D, Grunden JW, Klinghardt M, Patel VP, von Stockum S, Barnett C, Bitzer J.   +6 more
europepmc   +1 more source

Schedule‐dependent neuroprotection by pioglitazone in a novel model of α‐synucleinopathy in rats: Integrated behavioural and histological outcomes

British Journal of Pharmacology, EarlyView.
Background and Purpose α‐Synucleinopathies are neurodegenerative disorders characterized by the aggregation and propagation of misfolded α‐synuclein. In Parkinson's disease (PD), the most common α‐synucleinopathy, the progression of motor and nonmotor deficits, and dopaminergic neuron loss, are closely linked to the spreading of misfolded α‐synuclein ...
Alberto Santiago‐Balmaseda, Marcos M. Villegas‐Rojas, Isaac Pérez‐Segura, Maricela Espino‐Cambrón, Daniel Martinez‐Fong, Luis O. Soto‐Rojas   +5 more
wiley   +1 more source

Challenges to informed choice counselling: a qualitative study of contraceptive self-care introduction in the Copperbelt Province of Zambia. [PDF]

BMJ Glob Health
Cover J, Corneliess C, Mutesa M.
europepmc   +1 more source

A novel selective stabilizer of the ryanodine receptor 2 prevents stress‐induced ventricular arrhythmias without impairing cardiac function

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Aberrant activation of type 2 ryanodine receptors (RyR2) causes lethal arrhythmias, such as catecholaminergic polymorphic ventricular tachycardia (CPVT). Developing drugs that suppress RyR2 hyperactivation may be key to novel arrhythmia treatments.
Nagomi Kurebayashi, Masami Kodama, Hana Inoue, Masato Konishi, Masami Sugihara, Takashi Murayama, Ryosuke Ishida, Koichiro Ishii, Shuichi Mori, Yukari Endo, Xi Zeng, Yukiko U. Inoue, Takayoshi Inoue, Satoru Noguchi, Hajime Nishio, Eri Nakashima, Norio Suzuki, Noriko Nakaya, Ryushi Sato, Yuya Otori, Ayuna Tsutsumi, Mirei Takahashi, Takayuki Oka, Haruo Ogawa, Kayoko Kanamitsu, Hiroyuki Kusuhara, Utako Yokoyama, Junko Kurokawa, Hiroyuki Kagechika, Takashi Sakurai   +29 more
wiley   +1 more source

Changes in androgen profile over the menstrual cycle and hormonal contraceptive phases in physically active females. [PDF]

BMC Womens Health
Salmi VM, Mikkonen RS, Löfberg IE, McNulty KL, Hicks KM, Hackney AC, Ihalainen JK.   +6 more
europepmc   +1 more source

Diltiazem N‐oxide, a novel ischaemia‐activated prodrug, prevents ischaemia‐induced ventricular fibrillation without off‐target adverse effects

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Ventricular fibrillation (VF) in coronary heart disease accounts for up to 70% of sudden cardiac death. We examined whether diltiazem N‐oxide (DNO) has ischaemia‐selective antiarrhythmic activity. Experimental Approach Randomised and blinded experiments were performed in rat isolated hearts and in anaesthetised rats to ...
Louise M. Hesketh, Gabriel A. Watson, Francesca Mazzacuva, Zoe Hoare, Thomas R. Eykyn, Michael J. Curtis   +5 more
wiley   +1 more source

The violence of reproductive injustice: Reflections on birth control and its medical epistemics. [PDF]

Int J Equity Health
Niemann J, Glaum L, Jepsen D, Hofmann L, Schenk L, Führer A.   +5 more
europepmc   +1 more source

Fostamatinib treatment for patients with antiphospholipid syndrome and low platelet count: A case series

British Journal of Haematology, EarlyView.
Ekaterina Balaian, Rosa Sonja Alesci, Sandra Marten, Julia‐Annabell Georgi, Christiane Naue, Martin Bornhäuser, Karolin Trautmann‐Grill   +6 more
wiley   +1 more source