Hormonal contraceptives and body composition by use of stable isotope dilution techniques among women of reproductive age in Nyeri County, Kenya. [PDF]
PLoS OneLang'at PC +3 more
europepmc +1 more source
Hemophilia A: An Ideal Disease for Prenatal Therapy
Prenatal Diagnosis, EarlyView.ABSTRACT Hemophilia A (HA) is the most common inherited coagulation defect. Current state‐of‐the‐art treatment consists of frequent administration of prophylactic infusions of coagulation factor VIII (FVIII) protein or bispecific antibodies that replace the cofactor function of FVIIIa to maintain hemostasis. However, these treatments are far from ideal,
Christopher D. Porada +2 more
wiley +1 more source
Advances in Contraceptive Vaccine Development: A Comprehensive Review. [PDF]
Vaccines (Basel)Gao W, Shen X, Li P, Xiao C, Wang Y.
europepmc +1 more source
Advances in the Diagnosis, Treatment, and Management of Liver Nodules: A Comprehensive Review
Portal Hypertension &Cirrhosis, EarlyView.Liver nodules commonly occur due to various causes, some of which are malignant or may undergo malignant transformation, leading to disease progression or delayed detection in clinical practice. The widespread use of imaging methods has increased the detection rate of liver nodules. Furthermore, precision medicine techniques and artificial intelligence
Chang Gao, Dongyang Chen, Youpeng Chen
wiley +1 more source
Detection of Problems Related to Hormonal Contraceptives in Community Pharmacy: Application of a Structured Questionnaire in Women of Childbearing Age. [PDF]
Pharmacy (Basel)Sicilia-González R +5 more
europepmc +1 more source
Hormonal Contraceptives and Depression: A Proteomic Analysis Using Neuronal Models
PROTEOMICS – Clinical Applications, EarlyView.ABSTRACT Purpose Hormonal contraceptives are linked to a higher prevalence of depressive symptoms. Given their popularity in Western countries, understanding the biochemical effects on neuronal cells is crucial to minimizing mental health risks. Experimental Design Neural progenitor cells were treated with ethinyl estradiol (EE) and levonorgestrel (LNG)
Sam Thilmany +7 more
wiley +1 more source
Rescue of male infertility by human PRSS55 in transgenic mice establishes a contraceptive research model. [PDF]
Sci RepSutton CM +6 more
europepmc +1 more source
CPT: Pharmacometrics &Systems Pharmacology, EarlyView.ABSTRACT This study demonstrates the application of a model based meta analysis (MBMA) framework to characterize the safety and efficacy profiles of therapies in relapsed and refractory multiple myeloma (RRMM). Published clinical trial data were analyzed to evaluate the incidence of Grade ≥ 3 neutropenia and overall response rate (ORR), providing a ...
Zeel Shah +8 more
wiley +1 more source
The role of social networks in motivating access and use of contraceptives among adolescent girls and young women living in resource-constrained settings in Cape Town, South Africa. [PDF]
Reprod HealthTolla T +5 more
europepmc +1 more source
Long‐term remission in gout: Challenges and future opportunities
Rheumatology &Autoimmunity, EarlyView.Prolonged hyperuricemia is a major risk factor for gout, which is now regarded as a curable disease. Awareness of the various factors that can trigger gout flares is essential for their prevention. An important determinant of treatment decisions and long‐term follow‐up is the quality of the clinician–patient relationship. The “treat‐to‐target” approach
Patapong Towiwat, Zhanguo Li
wiley +1 more source