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Journal of Developmental and Physical Disabilities, 1982 The discovery by the Chinese scientists of gossypol as a male fertility regulating agent constitutes a major lead in male contraception. Gossypol is a polyphenolic compound present in the seed of the glandular variety of the cotton plant. Most of the basic and clinical studies in China and in other countries more recently, have been carried out with ...
M. R. N. Prasad, E. Diczfalusy
exaly +4 more sources
Gossypol detoxification in the rumen and Helicoverpa armigera larvae: A review
Animal Nutrition, 2021 Gossypol, a phenolic compound found in the cotton plant, is widely distributed in cottonseed by-products. Although ruminant animals are believed to be more tolerant of gossypol toxicity than monogastric animals due to rumen microbial fermentation, the ...
Wei-Kang Wang +2 more
exaly +3 more sources
Presence of free gossypol in whole cottonseed [PDF]
EFSA Journal, 2017 The European Commission asked EFSA to assess information provided by the Spanish Ministry of Agriculture, Food and Environment, on the toxicity of free gossypol in relation to the use of whole cotton seed in feed for ruminants, in particular dairy cows ...
EFSA Panel on Contaminants in the Food Chain (CONTAM) +22 more
doaj +2 more sources
The reversible effects of gossypol toxicity on male pigeons' reproductive performance [PDF]
Veterinary World, 2022 Background and Aim: Gossypol, a cotton seed derivative, is well known for its reversible antifertility in male reproduction across species. Its antifertility and reversibility effects on male reproductive function vary among species in dose-and time ...
Suwarak Wannaratana +3 more
doaj +1 more source
Protective Effect of Quercetin and Curcumin against Ovarian Oxidative Stress Induced by Gossypol in Albino Female Rats [PDF]
Journal of Applied Veterinary Sciences, 2022 This study aimed to investigate the effect of gossypol on ovarian physiology, which includes oxidative stress, hormone levels, and ovarian apoptosis, and detect the positive role of quercetin and curcumin against gossypol's effect.
Mahmood Abdullah, Fadwa Tawfeeq
doaj +1 more source
Shipin gongye ke-ji, 2022 Objective: The purpose of this study was to isolate bacteria capable of degrading gossypol and study their growth and degradation characteristics and detoxification effect on gossypol in cottonseed meal, which provided basis for further study on the ...
Feng WANG +8 more
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Effect of dietary cotton stalk on nitrogen and free gossypol metabolism in sheep [PDF]
Asian-Australasian Journal of Animal Sciences, 2019 Objective This study was to investigate the effects of dietary cotton stalk on nitrogen and free gossypol in sheep. Methods Treatments included 25% cotton stalk (Treat 1), 50% cotton stalk (Treat 2), and a control (no cotton stalk).
Halidai Rehemujiang +2 more
doaj +1 more source
Cotton roots are the major source of gossypol biosynthesis and accumulation
BMC Plant Biology, 2020 Background Gossypol is a specific secondary metabolite in Gossypium species. It not only plays a critical role in development and self-protection of cotton plants, but also can be used as important anti-cancer and male contraceptive compound.
Tianlun Zhao +7 more
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Gossypol improves myocardial dysfunction caused by sepsis by regulating histone acetylation
Clinical and Translational Science, 2023 Gossypol is a polyphenol from the cotton plant with anti‐inflammatory and anti‐oxidation activities and can also function as a histone deacetylase (HDAC) inhibitor. Sepsis is an inflammatory disease with high mortality.
Xiaohui Shi, Xinwei Lv, Dong Xiao
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Prenatal Exposure to Gossypol Impairs Corticogenesis of Mouse
Frontiers in Neuroscience, 2020 Gossypol is a yellow polyphenolic compounds extracted from roots, stems and seeds of cotton plants. Excessive intake of gossypol induces severe pathological signs of toxicity in livestock and wildlife.
Xiaoyan Zhu +6 more
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