Biochemical and metabolic responses of cotton variety XLZ54 to Thrips tabaci and screening of resistance characterization indicators. [PDF]
Pest Manag SciCotton varieties resistant to Thrips tabaci exhibit lower soluble sugar and free amino acid levels, with smaller post‐infestation increases in these nutrients, resulting in reduced feeding rates and lighter damage. Key resistance evaluation indices include: damage severity, soluble sugars, free amino acids, soluble proteins, superoxide dismutase ...
Guo X, Fan Z, Zhang J, Zhang H, Ma D.
europepmc +2 more sources
Screening of a Gossypol-Removing Yeast Strain and Characterization of Its Removal Mechanism [PDF]
MicroorganismsGossypol, a polyphenolic naphthalene derivative and yellow polyphenolic pigment found in cotton seed glands, presents notable environmental, animal, and human health hazards.
Yushuo Zhang +5 more
doaj +2 more sources
CRISPR/Cas9-mediated mutation of GhCAD decreases the gossypol content of cottonseed [PDF]
Journal of Biological EngineeringCottonseed is the most important byproduct of cotton production. However, high free gossypol contents limit the application of cottonseed in the food or feed industry.
Lili Zhou +8 more
doaj +2 more sources
Molecular Target Identification of Gossypol Against Cervical Cancer Based on Target Fishing Technology [PDF]
PharmaceuticsObjectives: This study aims to investigate the impact of Gossypol on human cervical cancer cells and elucidate its mechanism of action to establish a foundation for further clinical investigations.
Jinyan Li +6 more
doaj +2 more sources
Asian Pacific Journal of Tropical Biomedicine, 2021 Objective: To isolate, purify, and characterize gossypol from the fruits of Thespesia populnea (L) Sol. ex Correa, test its anti- dermatophytic activity, identify its targets on the dermatophyte, and confirm the binding of gossypol with the fungal target
R Anuthara +2 more
doaj +1 more source
(±)-Gossypol induces apoptosis and autophagy in head and neck carcinoma cell lines and inhibits the growth of transplanted salivary gland cancer cells in BALB/c mice [PDF]
, 2016 Racemic Gossypol [(±)-GOS], composed of both (-)-GOS and (+)-GOS, is a small BH3-mimetic polyphenol derived from cotton seeds. (±)-GOS has been employed and well tolerated by cancer patients. Head and neck carcinoma (HNC) represents one of the most fatal
Andracchio, Orlando +10 more
core +1 more source
Small molecule and peptide inhibitors of the pro-survival protein Mcl-1 [PDF]
, 2016 The ability of protein–protein interactions to regulate cellular processes in both beneficial and detrimental ways has made them obvious drug targets.
Beekman, Andrew, Howell, Lesley
core +1 more source
BMC Plant Biology, 2023 Background Gossypol is a unique secondary metabolite and sesquiterpene in cotton, which is mainly synthesized in the root system of cotton and exhibits many biological activities.
Kun Ye +4 more
doaj +1 more source
Gossypol Suppresses Growth of Temozolomide-Resistant Glioblastoma Tumor Spheres
Biomolecules, 2019 Temozolomide is the current first-line treatment for glioblastoma patients but, because many patients are resistant to it, there is an urgent need to develop antitumor agents to treat temozolomide-resistant glioblastoma.
Hee Yeon Kim +8 more
doaj +1 more source
PLoS ONE, 2020 The tolerance of ruminants to gossypol, a natural phenolic compound derived from the cotton plant, is greater than that of monogastric animals, partially because of the gossypol-degrading bacteria in the rumen of the ruminants. In this study, we aimed to
CaiDie Wang +4 more
doaj +1 more source