Results 11 to 20 of about 6,673 (189)

The embryotoxicity of gossypol [PDF]

open access: yesTeratology, 1985
AbstractIn utero development was analyzed in pregnancies that resulted from matings between gossypol‐treated male rats and untreated female rats and in pregnancies in which gossypol was administered to the pregnant rat only. Gossypol treatment of males had no effect on the outcome of pregnancy.
Beaudoin, Allan R., Allan R. Beaudoin
openaire   +5 more sources

Effect of dietary gossypol supplement on fermentation characteristics and bacterial diversity in the rumen of sheep.

open access: yesPLoS ONE, 2020
The tolerance of ruminants to gossypol, a natural phenolic compound derived from the cotton plant, is greater than that of monogastric animals, partially because of the gossypol-degrading bacteria in the rumen of the ruminants. In this study, we aimed to
CaiDie Wang   +4 more
doaj   +2 more sources

Gossypol Toxicity from Cottonseed Products [PDF]

open access: yesThe Scientific World Journal, 2014
Gossypol is a phenolic compound produced by pigment glands in cotton stems, leaves, seeds, and flower buds (Gossypium spp.). Cottonseed meal is a by-product of cotton that is used for animal feeding because it is rich in oil and proteins.
Ivana Cristina N. Gadelha   +4 more
doaj   +2 more sources

Gossypol Suppresses Growth of Temozolomide-Resistant Glioblastoma Tumor Spheres [PDF]

open access: yesBiomolecules, 2019
Temozolomide is the current first-line treatment for glioblastoma patients but, because many patients are resistant to it, there is an urgent need to develop antitumor agents to treat temozolomide-resistant glioblastoma.
Hee Yeon Kim   +8 more
doaj   +3 more sources

GOSSYPOL PROMOTES THE DEGENERATION OF CHICKEN OVARIAN FOLLICLES IN VITRO

open access: yesBrazilian Journal of Poultry Science
Gossypol, a phenolic compound produced by the pigment glands of cotton, is known to affect male reproduction. In females, exposure to gossypol has been associated with interference with the estrous cycle and embryo development.
ICN Gadelha   +3 more
doaj   +2 more sources

A Spin-Labeled Derivative of Gossypol

open access: yesMolecules
Gossypol and its derivatives arouse interest due to their broad spectrum of biological activities. Despite its wide potential application, there is no reported example of gossypol derivatives bearing stable radical functional groups.
Andrey V. Stepanov   +8 more
doaj   +2 more sources

Presence of free gossypol in whole cottonseed [PDF]

open access: yesEFSA Journal, 2017
The European Commission asked EFSA to assess information provided by the Spanish Ministry of Agriculture, Food and Environment, on the toxicity of free gossypol in relation to the use of whole cotton seed in feed for ruminants, in particular dairy cows ...
EFSA Panel on Contaminants in the Food Chain (CONTAM)   +22 more
doaj   +5 more sources

Biodegradation of Gossypol by Aspergillus terreus-YJ01

open access: yesMicroorganisms, 2023
Gossypol, generally found in the roots, stems, leaves, and, especially, the seeds of cotton plants, is highly toxic to animals and humans, which inhibits the use of cotton stalks as a feed resource.
Yao Jiang   +7 more
doaj   +2 more sources

Gossypol improves myocardial dysfunction caused by sepsis by regulating histone acetylation

open access: yesClinical and Translational Science, 2023
Gossypol is a polyphenol from the cotton plant with anti‐inflammatory and anti‐oxidation activities and can also function as a histone deacetylase (HDAC) inhibitor. Sepsis is an inflammatory disease with high mortality.
Xiaohui Shi, Xinwei Lv, Dong Xiao
doaj   +1 more source

Prenatal Exposure to Gossypol Impairs Corticogenesis of Mouse

open access: yesFrontiers in Neuroscience, 2020
Gossypol is a yellow polyphenolic compounds extracted from roots, stems and seeds of cotton plants. Excessive intake of gossypol induces severe pathological signs of toxicity in livestock and wildlife.
Xiaoyan Zhu   +6 more
doaj   +1 more source

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