Results 31 to 40 of about 35,949 (266)
The impact of freedom on fertility decline. [PDF]
, 2013 Although fertility decline often correlates with improvements in socioeconomic conditions, many demographers have found flaws in demographic transition theories that depend on changes in distal factors such as increased wealth or education.
Campbell, Martha +2 more
core +2 more sources
Gamendazole, an Orally Active Indazole Carboxylic Acid Male Contraceptive Agent, Targets HSP90AB1 (HSP90BETA) and EEF1A1 (eEF1A), and Stimulates Il1a Transcription in Rat Sertoli Cells1 [PDF]
Biology of Reproduction, 2008 Gamendazole was recently identified as an orally active antispermatogenic compound with antifertility effects. The cellular mechanism(s) through which these effects occur and the molecular target(s) of gamendazole action are currently unknown. Gamendazole was recently designed as a potent orally active antispermatogenic male contraceptive agent.
Joseph S. Tash +11 more
openaire +3 more sources
Contribution of recent transgenic models and transcriptional profiling studies to our understanding of the mechanisms by which androgens control spermatogenesis [PDF]
, 2008 Publisher ...
Claessens, Frank +7 more
core +1 more source
Gates Open Research, 2019 Background: Male engagement is becoming more common in family planning (FP) strategies and interventions, yet effective monitoring and evaluation (M&E) of this approach lags. This review sought to understand how male engagement in FP is defined, identify
Bridgit M. Adamou +3 more
doaj +1 more source
The effect of the male contraceptive agent Gossypol on human lymphocytes in vitro: traditional chromosome breakage, micronuclei, sister chromatid exchange, and cell kinetics. [PDF]
Journal of Medical Genetics, 1983 The male antifertility agent Gossypol did not affect the level of traditional chromosome breakage or number of micronuclei in 66-hour lymphocyte cultures at concentrations up to 40 micrograms/ml. It did increase the frequency of SCE slightly, although the inter-individual variation was greater than the increase resulting from Gossypol, and, even at the
Y C, Tsui, M R, Creasy, M A, Hultén
openaire +2 more sources
BMC Infectious Diseases, 2008 Background Youth have been reported to be at a higher risk of acquiring STIs with significant adverse health and social consequences. Knowledge on the prevailing risky practices is an essential tool to guide preventive strategies.
Mhalu F +4 more
doaj +1 more source
Reproductive Health, 2019 Background Inadequate infrastructure, security threats from ongoing armed conflict, and conservative socio-cultural and gender norms that favour large families and patriarchal power structures contribute to poor sexual and reproductive health (SRH ...
Victoria J. Steven +6 more
doaj +1 more source
The FASEB Journal, 2014 The non‐hormonal male contraceptive H2‐gamendazole (H2‐GMZ) is a lonidamine derivative that has been shown to accumulate in rat testes at levels about 10 times higher than in the liver and other organs. Given that H2‐GMZ is an organic anion with a molecular weight of more than 400 Da, it could interact with Organic Anion Transporting Polypeptides ...
Jessica Shoop +7 more
openaire +1 more source
Reversible Contraception in Males: An Obtainable Target?
BiologyThe last few decades have brought contraception to the forefront of research, with great strides made in effectively targeting and optimizing the physiology, pharmacology, and delivery processes that prevent pregnancy.
Joanna Nandita Koilpillai +4 more
doaj +1 more source
Arthritis Care &Research, EarlyView.People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley +1 more source