Results 71 to 80 of about 11,746 (198)

Harnessing Free Radical Scavenging Potential of Caffeic Acid as a Nutraceutical—A Review

Food Safety and Health, EarlyView.
Caffeic acid has emerged as a promising bioactive molecule with multiple pharmacological properties, including antioxidant, antimicrobial, anti‐inflammatory, organ protective properties and metal‐chelating ability. This review emphasizes the dietary sources, structural characteristic, molecular mechanism underlying health promoting effects of caffeic ...
Pavitra Behra, Monika Bhadauria, Satendra Kumar Nirala   +2 more
wiley   +1 more source

Perioperative Piperacillin/Tazobactam Reduces Early Onset SSI in Preirradiated Patients Undergoing Microvascular Head and Neck Reconstruction

Head &Neck, EarlyView.
ABSTRACT Background Preirradiated patients undergoing microvascular head and neck reconstruction for tumor recurrence or osteoradionecrosis (ORN) face surgical site infection (SSI) rates exceeding 30%. The impact of perioperative extended‐spectrum antibiotic coverage remains unclear. This study hypothesizes that calculated prophylaxis with piperacillin/
Johannes G. Schuderer, Florian Hoferer, Jonas Eichberger, Mathias Fiedler, André Gessner, Stilla Bauernfeind, Maximilian Gottsauner, Felix Nieberle, Michael Maurer, Johannes K. Meier, Torsten E. Reichert, Tobias Ettl   +11 more
wiley   +1 more source

Toward a Typology of Patients With Head and Neck Cancer: Biopsychosocial Profiles Predicting Longitudinal Quality of Life

Head &Neck, EarlyView.
ABSTRACT Background Quality of life (QoL) in head and neck cancer (HNC) is influenced by complex biopsychosocial factors, yet few longitudinal studies have examined these relationships immediately post‐treatment. Methods In this prospective study, 232 patients newly diagnosed with primary HNC completed psychometric assessments, clinical interviews, and
Haley Deamond, Cyril Devault‐Tousignant, Jacob Lang, Christopher Lo, Jennifer Silver, Nader Sadeghi, Zeev Rosberger, Saul Frenkiel, Michael Hier, Anthony Zeitouni, Karen Kost, Alex Mlynarek, Keith Richardson, Gabrielle Chartier, Marco Mascarella, Khalil Sultanem, Georges Shenouda, Fabio Cury, Melissa Henry   +18 more
wiley   +1 more source

Influenza and Human Papillomavirus Vaccine Utilisation in Vulnerable Urban Youth in Edmonton, Alberta, Canada

The International Journal of Health Planning and Management, EarlyView.
ABSTRACT Introduction This project explores influenza and human papillomavirus (HPV) vaccine utilisation among a multi‐ethnic group of youth (aged 11–23 years) in Edmonton, Alberta, Canada. Method Using a cross‐sectional design and purposive sampling, influenza vaccine utilisation over 3 years was assessed via questionnaire.
Sarah Deck, Se Lim Jang, Rachel Harris, Fariba Kolahdooz, Moutasem Zakkar, Sangita Sharma   +5 more
wiley   +1 more source

Tolerability and efficacy of chemosaturation in combination with systemic therapy for metastatic uveal melanoma

International Journal of Cancer, EarlyView.
What's New? Uveal melanoma is the most common primary intraocular cancer in adults, and up to half of patients develop metastatic disease, predominantly in the liver, where prognosis remains poor despite promising treatment options. In this study, the authors evaluated the safety and efficacy of administering systemic therapy within 40 days of liver ...
Patrick Kasteleiner, Gerd Grözinger, Jörg Schmehl, Lukas Flatz, Andrea Forschner   +4 more
wiley   +1 more source

Interventions addressing violence against women in health services: An overview of systematic reviews regarding barriers and facilitators to implementation

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Violence against women is a global issue rooted in gender inequities, requiring coordinated responses within the healthcare system. However, both providers and users face significant challenges in effectively implementing interventions to address it.
Odette del Risco Sánchez, Larissa Rodrigues, Erika Zambrano, Fernanda Garanhani Surita   +3 more
wiley   +1 more source

Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae

Interdisciplinary Medicine, EarlyView.
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang, Zhuolin Li, Yang Yang, Zihan He, Tyuji Hoshino, Vladislav Victorovich Khrustalev, Qing Zhu, Weiling Wu, Wei Zhao, Chenguang Shen, Shi Ouyang   +10 more
wiley   +1 more source

Ivermectin Toxicity in Humans and Animals: Clinical Spectrum, Mechanisms, and Management

Journal of Applied Toxicology, EarlyView.
ABSTRACT Ivermectin is a widely used macrocyclic lactone with established efficacy against a broad range of parasitic infections in humans and animals and a long‐standing reputation for clinical safety. However, increasing evidence indicates that ivermectin can produce clinically relevant toxicity under specific conditions, particularly involving the ...
Serkan Yilmaz, Bayram Göktaş, İlker Ateş, Mustafa Çelik   +3 more
wiley   +1 more source

Impact of COVID‐19 Pandemic on Antibiotic Resistance Patterns of Common Bacterial Pathogens to Antibiotics in Northern Ghana

Journal of Clinical Laboratory Analysis, EarlyView.
This retrospective study analyzed and compared antimicrobial resistance patterns of common bacterial pathogens before (October 2018–March 2020) and during (April 2020–December 2022) the COVID‐19 pandemic in Ghana's Northern Region. Amoxiclav (p = 0.027), ceftazidime (p = 0.002), ciprofloxacin (p = 0.001), gentamycin (p = 0.035), and meropenem (p < 0 ...
Hisham Alhassan Osumanu, Oliver Nangkuu Deberu, Abass Abdul‐Karim, Ahmed Alhassan, Ebenezer Kojo Addae, Stephen Opoku Afriyie, Stebleson Azure, Sadia Alimatu Lawal, Daron Davies Agboyie, Valentine Cheba Koyiri, Hudu Yakubu, Enoch Weikem Weyori, Kennedy Mensah Osei, Benjamin Demah Nuertey, Godfred Acheampong   +14 more
wiley   +1 more source

Comparative Outcomes of Endoscopic Treatment for Symptomatic and Asymptomatic Common Bile Duct Stones in the Elderly: A Propensity Score‐Based Cohort Analysis

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Introduction Various guidelines recommend endoscopic stone removal for asymptomatic common bile duct stones (CBDS); however, previous studies have indicated that asymptomatic CBDS is associated with a higher incidence of post‐ERCP pancreatitis (PEP).
Kota Shimojo, Akinori Maruta, Keisuke Iwata, Yuhei Iwasa, Mitsuru Okuno, Kensaku Yoshida, Shinya Uemura, Tsuyoshi Mukai, Takuji Iwashita, Masahito Shimizu   +9 more
wiley   +1 more source