Three-phase generalized raking and multiple imputation estimators to address error-prone data [PDF]
Validation studies are often used to obtain more reliable information in settings with error-prone data. Validated data on a subsample of subjects can be used together with error-prone data on all subjects to improve estimation. In practice, more than one round of data validation may be required, and direct application of standard approaches for ...
arxiv
Sexual health knowledge, attitudes and behaviour of Sāmoan youth in Aotearoa New Zealand : a thesis presented in fulfilment of the requirements for the degree of Doctor of Philosophy in Public Policy at Massey University, Albany, New Zealand [PDF]
Sex and sexuality in many cultures are sensitive topics. For many Pacific communities where sex is often regarded as tapu (sacred), cultural and religious values largely frame how sexuality and pregnancy are understood.
Veukiso-Ulugia, Analosa
core
The impact of freedom on fertility decline. [PDF]
Although fertility decline often correlates with improvements in socioeconomic conditions, many demographers have found flaws in demographic transition theories that depend on changes in distal factors such as increased wealth or education.
Campbell, Martha+2 more
core +2 more sources
This study introduces KK2DP7, a dendrimer‐structured peptide adjuvant, as a tool to decode trained immunity's role in antitumor therapy. Splenic CD11b+ cells mediate tumor suppression via TLR2‐IRF7 activation and epigenetic reprogramming, validated by adoptive transfer experiments.
Rui Zhang+5 more
wiley +1 more source
A Comprehensive Study of Gender Bias in Chemical Named Entity Recognition Models [PDF]
Chemical named entity recognition (NER) models are used in many downstream tasks, from adverse drug reaction identification to pharmacoepidemiology. However, it is unknown whether these models work the same for everyone. Performance disparities can potentially cause harm rather than the intended good.
arxiv
Synthetic gene circuits regulated by bezafibrate are developed to express tumor antigens and PD‐L1 nanobody (PD‐L1nb), enhancing cancer immunotherapy. Delivered via HEK293T cells, ESCs, or directly injected the plasmids containing the circuit into the tumor, the circuits reduce tumor growth, boost CD8+ T cells, and minimize T cell exhaustion.
Meiling Jin+3 more
wiley +1 more source
Sensemaking About Contraceptive Methods Across Online Platforms [PDF]
Selecting a birth control method is a complex healthcare decision. While birth control methods provide important benefits, they can also cause unpredictable side effects and be stigmatized, leading many people to seek additional information online, where they can find reviews, advice, hypotheses, and experiences of other birth control users.
arxiv
Effect of oral contraceptive agents on ascorbic acid metabolism in the rhesus monkey.
Ascorbic acid (AA) metabolism was studied in six sexually mature female rhesus monkeys with normal menstrual cycles before and during oral contraceptive administration.
J. Weininger, J. King
semanticscholar +1 more source
Novel Bivalent mRNA‐LNP Vaccine for Highly Effective Protection against Pneumonic Plague
The study investigates mRNA‐lipid nanoparticle vaccines targeting Yersinia pestis, the causative agent of plague. Combined F1+LcrV mRNA vaccination elicited robust immune responses and protected mice against virulent wild‐type and atypical strains.
Uri Elia+12 more
wiley +1 more source
The Risk of Venous Thromboembolism Associated with Oral Contraceptive; the Search Is Still On
A few years after coming to the market, the first generation of oral contraceptive pills (OCPs) were linked to significant risk of venous thromboembolism (VTE). This increased risk was blamed on the presence of the estrogen-like compounds in these agents.
Ali Abdalvand
doaj +1 more source