Results 101 to 110 of about 22,694 (264)
What anabolic–androgenic steroids reveal about the limits of current harm reduction models
Addiction, EarlyView.Abstract Background Harm reduction has largely been shaped by responses to psychoactive drug use where the most urgent harms are acute. These models focus on overdose, blood‐borne viruses, and rapid‐onset toxicity related harms. When applied wholesale to anabolic–androgenic steroids (AAS), they obscure the distinctive pharmacology, consumer typologies,
Timothy Piatkowski +2 more
wiley +1 more source
Allergy, EarlyView.ABSTRACT Hereditary angioedema (HAE) with C1 inhibitor deficiency is a rare disease characterized by unpredictable episodes of tissue swelling (angioedema), which, in most cases, occur first under the age of 18 years, and entail a significant burden of disease not only for the patients but also for their families.
Henriette Farkas +128 more
wiley +1 more source
Allergy, EarlyView.ABSTRACT This update and revision of the international guideline for urticaria was developed in accordance with the methods recommended by Cochrane and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. It is an initiative of the Global Allergy and Asthma Excellence Network (GA2LEN) and its Urticaria and ...
T. Zuberbier +221 more
wiley +1 more source
Andrology, EarlyView.ABSTRACT Background Klinefelter syndrome is associated with a markedly increased risk of venous thrombosis. While hypogonadism and metabolic dysfunction are known contributors, the role of the contact activation system in Klinefelter syndrome remains unexplored.
Simon Chang +4 more
wiley +1 more source
Andrology, EarlyView.ABSTRACT Background Retinoic acid plays a critical role in spermatogenesis during both spermatogonial differentiation and spermiation. Mice lacking enzymes that synthesize retinoic acid, Aldh1a1/1a2, in the testes are infertile. WIN 18,446 reversibly inhibits spermatogenesis by inhibiting ALDH1A1/1A2 and is a promising approach to male contraception ...
Jisun Paik +3 more
wiley +1 more source
Acta Obstetricia et Gynecologica Scandinavica, EarlyView.Endometriosis (including adenomyosis) is an inflammatory disease with lesions of endometrial tissue outside the uterus or in the uterine wall. In this study on Swedish women, endometriosis or adenomyosis was associated with persistently increased risks of breast and epithelial ovarian cancers, especially clear cell, endometrioid, and low‐grade serous ...
Louise Moberg +6 more
wiley +1 more source
Menopausal hormone therapy after ovarian cancer: A 10‐year survival analysis in premenopausal women
Acta Obstetricia et Gynecologica Scandinavica, EarlyView.Among premenopausal women surgically treated for ovarian cancer, no difference in 10‐year overall survival was observed between postoperative MHT users and non‐users. Young ovarian cancer survivors should be recommended MHT after surgically induced menopause.
Åsa Ehlin von Kartaschew +4 more
wiley +1 more source
Acta Obstetricia et Gynecologica Scandinavica, EarlyView.Noninferiority of opportunistic salpingectomy during benign hysterectomy compared with hysterectomy‐only concerning ovarian function measured by anti‐Müllerian hormone 1 year after surgery could not be declared. Studies with clinical outcomes related to ovarian function are still needed.
Anna Darelius +3 more
wiley +1 more source
Acta Obstetricia et Gynecologica Scandinavica, EarlyView.Immediate intrauterine device placement after second‐trimester medical abortion was associated with a higher incidence of expulsion, lower use of IUD at 12 months, and lower acceptance compared with delayed placement. However, no significant increase in subsequent pregnancies or abortions was observed at the 12 month follow‐up.
Sara Hogmark +4 more
wiley +1 more source
Acta Paediatrica, EarlyView.ABSTRACT Aim This Prospective, Community‐Based Cohort Study Investigated Cardiovascular Health and Its Association With Low‐Grade Inflammation in Adolescents. Methods Data were collected by specially trained medical staff from 1379 Austrian adolescents aged 14–19 years from 3 February 2021 to 28 February 2023.
Katharina Mueller +6 more
wiley +1 more source