Results 1 to 10 of about 5,539 (231)

Long term use of oral contraceptives comprising synthetic estrogens induces an excessive breast cancer risk in BRCA mutation carrier women: a meta-analysis [PDF]

Clinical and Experimental Obstetrics & Gynecology, 2022
Background: The relationship between oral contraceptive (OC) use and breast cancer risk is highly debated. Recent publications support a slight increase in overall breast cancer risk among OC user women, in particular among the current users.
Hongling Peng, Xiaorong Qi, Qiao Wang
doaj   +2 more sources

Dienogest vs. combined oral contraceptive: A systematic review and meta‐analysis of efficacy and side effects to inform evidence‐based guidelines [PDF]

Acta Obstetricia et Gynecologica Scandinavica
Introduction Dienogest is a synthetic fourth‐generation progestin that has been approved for the medical treatment of endometriosis, and its efficacy on pain symptoms and quality of life is well established even in the long term.
Ilaria Piacenti, Veronica Tius, Maria Federica Viscardi, Anna Biasioli, Martina Arcieri, Stefano Restaino, Ludovico Muzii, Giuseppe Vizzielli, Maria Grazia Porpora   +8 more
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Structure Based Virtual Docking and Molecular Dynamics Guided Identification of Potential Phytoconstituents from Traditionally Used Female Antifertility Plant [PDF]

Pharmaceutical Sciences, 2022
Background: Oral contraceptives are very widely used agents to check unwanted pregnancies.They contain synthetic analogues of estrogen and progesterone hormones. Estrogen is an important hormone that plays a significant role in menstrual cycle, ovulation,
Keerthi Priya, Suman Manandhar, Runali Sankhe, M Manjunath Setty, UV Babu, Sreedhara Ranganath Pai   +5 more
doaj   +1 more source

Do oral contraceptives affect young women’s memory? Dopamine-dependent working memory is influenced by COMT genotype, but not time of pill ingestion

PLoS ONE, 2021
Background Despite the widespread use of oral contraceptives (OCs), and the well-documented influence of estrogens, notably 17β-estradiol (E2), on cognition, research relating OCs to working memory is limited and mixed.
Laura Gravelsins, Katherine Duncan, Gillian Einstein   +2 more
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Evaluating the Cognitive Impacts of Drospirenone, a Spironolactone-Derived Progestin, Independently and in Combination With Ethinyl Estradiol in Ovariectomized Adult Rats

Frontiers in Neuroscience, 2022
Oral contraceptives and hormone therapies require a progestogen component to prevent ovulation, curtail uterine hyperplasia, and reduce gynecological cancer risk.
Stephanie V. Koebele, Stephanie V. Koebele, Mallori L. Poisson, Mallori L. Poisson, Justin M. Palmer, Justin M. Palmer, Claire Berns-Leone, Claire Berns-Leone, Steven N. Northup-Smith, Steven N. Northup-Smith, Veronica L. Peña, Veronica L. Peña, Isabel M. Strouse, Isabel M. Strouse, Haidyn L. Bulen, Haidyn L. Bulen, Shruti Patel, Shruti Patel, Corissa Croft, Corissa Croft, Heather A. Bimonte-Nelson, Heather A. Bimonte-Nelson   +21 more
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No Differences in Value-Based Decision-Making Due to Use of Oral Contraceptives

Frontiers in Endocrinology, 2022
Fluctuating ovarian hormones have been shown to affect decision-making processes in women. While emerging evidence suggests effects of endogenous ovarian hormones such as estradiol and progesterone on value-based decision-making in women, the impact of ...
Carolin A. Lewis, Carolin A. Lewis, Carolin A. Lewis, Ann-Christin S. Kimmig, Ann-Christin S. Kimmig, Nils B. Kroemer, Shakoor Pooseh, Shakoor Pooseh, Michael N. Smolka, Julia Sacher, Julia Sacher, Birgit Derntl   +11 more
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Complex questions about combined hormonal contraception: A review

Гинекология, 2023
Combined oral contraceptives (COCs) containing synthetic analogs of sex steroids are considered the most effective and popular method of contraception worldwide.
Vera N. Prilepskaya, Lana L. Bostandzhian   +1 more
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The Effect of a Synthetic Estrogen, Ethinylestradiol, on the hERG Block by E-4031

Biomolecules, 2021
Inhibition of K+-conductance through the human ether-a-go-go related gene (hERG) channel leads to QT prolongation and is associated with cardiac arrhythmias.
Fumiya Tamura, Shintaro Sugimoto, Mana Sugimoto, Kazuho Sakamoto, Masahiko Yamaguchi, Takeshi Suzuki, Keiichi Fukuda, Masaki Ieda, Junko Kurokawa   +8 more
doaj   +1 more source

Effects of orally administered hormonal contraceptives on the musculoskeletal system of healthy premenopausal women—A systematic review

Health Science Reports, 2022
Introduction The musculoskeletal system (MSK) is one of the extragonadal target tissues of sex hormones: osteoblasts and osteocytes express estrogen receptors, while in fibroblasts of the anterior cruciate ligament (ACL) and myocytes of the vastus ...
Claudia Römer, Julia Czupajllo, Bernd Wolfarth, Markus H. Lerchbaumer, Kirsten Legerlotz   +4 more
doaj   +1 more source

Detection of α-Ethinyl Estradiol in Water by Voltammetry: Mechanistic Study and Practical Implications

International Journal of Electrochemical Science, 2021
Residue amounts of synthetic estradiol; an active ingredient of oral contraceptives finds its way into water bodies. Estrogenic effects on aquatic life as well as on humans and other land animals are of great health concerns.
Zepeng Qian, Shashi Lalvani, Lei L. Kerr
doaj   +1 more source