Results 111 to 120 of about 14,451 (146)
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The metabolism of synthetic estrogens in non-users and users of oral contraceptives

Steroids, 1975
Using both pulse injections and constant infusions of 3-H-mestranol (3H-ME) (1) and 3-H-ethinyl estradiol (3H-EE) we have studied the metabolism of these compounds in non-users and users of oral contraceptives. Following pulse injection of 3-H-ME the disappearance of radioactivity could be described as a function which was the sum of two exponentials ...
Christopher Longcope   +1 more
openaire   +2 more sources

Neurological syndromes occurring in patients receiving synthetic steroids (oral contraceptives)

Neurology, 1966
Case studies of 34 women with neurological syndromes associated with oral contraceptive use are discussed with a view to identifying contraindications of progestational steroid use. The patients were classified by occlusive cerebral arterial disease (5 patients) cortical vein thrombosis (1 patient) and vascular headaches (28 patients).
Peritz Scheinberg, Sherif Shafey
openaire   +3 more sources

Occurrence, fate and removal of synthetic oral contraceptives (SOCs) in the natural environment: A review

Science of The Total Environment, 2011
Synthetic oral contraceptives (SOCs) are a group of compounds with progestagenic and/or androgenic activities, with some also possessing estrogenic activities. Recent research has documented that some of these emerging contaminants have adverse effects on aquatic organisms at very low concentrations.
Zehua Liu   +3 more
openaire   +3 more sources

Residual vascular risk of discontinued oral contraception

Atherosclerosis, 1985
Recent epidemiological data indicate that the risk of thromboembolic disease associated with oral contraception (OC) may persist after discontinuation of the drug. It was demonstrated on the other hand that antibodies to sex steroid hormones which develop in OC users, were significantly correlated with the incidence of thrombosis. It is well known that
F. Doucet   +3 more
openaire   +3 more sources

Embryotoxicity of Norlestrin, a combined synthetic oral contraceptive, in rhesus macaques (Macaca mulatta)

Teratology, 1983
AbstractThirty timed‐mated pregnant rhesus monkeys received Norlestrin (Norethindrone acetate, 2.5 mg, and ethinyl estradiol, 0.05 mg pertablet, Parke‐Davis) orally at four different dose levels. The dose levels were 5, 10, 25 and 50 mg/day/monkey and the doses were administered during early (days 21–35), late (days 33–46), and throughout (days 21–46 ...
Andrew G Hendrickx, S. Prahalada
openaire   +3 more sources

Steroid contraceptives in non-human primates (II) Metabolic fate of synthetic estrogens in the baboon exposure to oral contraceptives

Contraception, 1977
Abstract The metabolic fate of isotopically labelled ethynylestradiol (EE) and its 3-methyl ether, mestranol (MEE), was investigated in three baboons who were receiving a norethindrone-mestranol combination oral contraceptive (C.O.C.) and the results compared to those previously obtained from the same baboons before receiving the C.O.C.
T.D. Avila   +2 more
openaire   +3 more sources

Comparative studies on two combination oral contraceptives, one containing synthetic estrogen, the other “natural” estrogens

Contraception, 1978
Two combined oral contraceptives, one containing ethinyl estradiol and the other micronized estradiol and estriol, were compared by measuring a variety of endocrine and renal parameters over nine months. Significant changes were observed in plasma renin activity (P.R.A.) on the synthetic estrogen.
D.M. Saunders   +2 more
openaire   +3 more sources

SERUM LIPIDS AND LIPOPROTEINS DURING TREATMENT WITH ORAL CONTRACEPTIVES CONTAINING NATURAL AND SYNTHETIC OESTROGENS

Acta Endocrinologica, 1978
ABSTRACT Increases in serum triglycerides, cholesterol and pre-β- and β-lipoproteins have been considered as significant pathogenic factors regarding the possible thrombotic side-effect of treatment with oral contraceptives of the combined type containing synthetic oestrogen.
L. Hemmingsen   +4 more
openaire   +3 more sources

The estrogenic activity of synthetic progestins used in oral contraceptives enhances fatty acid synthase-dependent breast cancer cell proliferation and survival

International Journal of Oncology, 2005
Overexpression of the lipogenic enzyme fatty acid synthase (FAS) is a common molecular feature in subsets of sex-steroid-related tumors including breast carcinomas that is associated with poor prognosis. In this study, we explored whether breast-cancer associated FAS (oncogenic antigen-519) is regulated by the progestin component in oral contraceptives.
Bharvi P. Oza   +3 more
openaire   +3 more sources

Die Beeinflu�barkeit der Gonadotropinabsonderung durch den synthetisierten LH-Releasing-Faktor unter der Medikation eines Ovulationsblockers

Klinische Wochenschrift, 1973
Mit dem synthetisierten LH-Releasing-Faktor1 last sich in einer Dosis von 50 µg zwischen dem 22. und 26. Cyclustag eine LH- und FSH-Ausschuttung wie zur Zeit der Ovulation erzielen. Unter Gabe eines definierten Ovulationsblockers blieb bei den gleichen Frauen trotz LH-Releasing-Faktor in gleicher Dosis der zur Zeit der Ovulation beobachtete Anstieg der
A. Reuter   +3 more
openaire   +4 more sources

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