Results 151 to 160 of about 15,414 (282)

When Birth Control Turns Biliary: A Rare Case of Profound Hyperbilirubinemia From Oral Contraceptives. [PDF]

J Investig Med High Impact Case Rep
Ajani T, Calderon A, Loayza Pintado J, Derian N, Matos C, Mogollon I, Suarez A.   +6 more
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Management of women with hirsutism in Kosovo. [PDF]

Postepy Dermatol Alergol
Lumezi BG, Lokaj-Berisha V.
europepmc   +1 more source

Transcriptomic analysis reveals lipid metabolism and macrophage involvement associated with nintedanib treatment in a rat bleomycin model

British Journal of Pharmacology, EarlyView.
In this study, nintedanib reduced lung fibrosis in a rat double‐hit bleomycin‐induced model. Transcriptomic analysis revealed two key gene signatures related to the effect of the molecule: one involving mesenchymal cells affecting known fibrotic pathways and another linking mainly macrophages to lipid metabolism.
Martina Bonatti, Vanessa Pitozzi, Paola Caruso, Silvia Pontis, Maria Gloria Pittelli, Caterina Frati, Denise Madeddu, Federico Quaini, Costanza Anna Maria Lagrasta, Ilaria Minato, Emanuela Bocchi, Maurizio Civelli, Gino Villetti, Marcello Trevisani, Barbara Montanini   +14 more
wiley   +1 more source

Olfactory perception and wellbeing across hormonal contraceptive users and menstrual cycle phases. [PDF]

Front Hum Neurosci
Gonçalves PMR, de Azevedo BC, Fomin D, Galeazzo RG, Veiga CA, Rezende NQ, Siba IP, Pascarelli RGB, Dieamant G, Podgaec S, Pinheiro CH.   +10 more
europepmc   +1 more source

A novel selective stabilizer of the ryanodine receptor 2 prevents stress‐induced ventricular arrhythmias without impairing cardiac function

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Aberrant activation of type 2 ryanodine receptors (RyR2) causes lethal arrhythmias, such as catecholaminergic polymorphic ventricular tachycardia (CPVT). Developing drugs that suppress RyR2 hyperactivation may be key to novel arrhythmia treatments.
Nagomi Kurebayashi, Masami Kodama, Hana Inoue, Masato Konishi, Masami Sugihara, Takashi Murayama, Ryosuke Ishida, Koichiro Ishii, Shuichi Mori, Yukari Endo, Xi Zeng, Yukiko U. Inoue, Takayoshi Inoue, Satoru Noguchi, Hajime Nishio, Eri Nakashima, Norio Suzuki, Noriko Nakaya, Ryushi Sato, Yuya Otori, Ayuna Tsutsumi, Mirei Takahashi, Takayuki Oka, Haruo Ogawa, Kayoko Kanamitsu, Hiroyuki Kusuhara, Utako Yokoyama, Junko Kurokawa, Hiroyuki Kagechika, Takashi Sakurai   +29 more
wiley   +1 more source

Hormonal Contraceptive Formulations and Breast Cancer Risk in Adolescents and Premenopausal Women. [PDF]

JAMA Oncol
Hadizadeh F, Koteci A, Karlsson T, Ek WE, Johansson Å.   +4 more
europepmc   +1 more source

Update on Menopause Hormone Therapy; Current Indications and Unanswered Questions

Clinical Endocrinology, EarlyView.
ABSTRACT Objective To provide clinicians involved in managing menopause with a summary of current evidence surrounding menopause hormone therapy (MHT). Design The authors evaluate and synthesize existing pooled evidence relating to MHT's clinical indications, efficacy, and safety and explore the limitations of existing data. Patients The review focuses
Annice Mukherjee, Susan R. Davis
wiley   +1 more source

Oral contraceptives exposure may reduce the risk of ovarian cancer: a meta-analysis based on cohort studies. [PDF]

Front Pharmacol
Sun Q, Ji J, Chen J, Jiang T, Zhang S, Yang H.   +5 more
europepmc   +1 more source

The Relationship Between Polycystic Ovary Syndrome (PCOS) and Depression

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder, frequently accompanied by psychological comorbidities including depression. The aim of this narrative review is to summarise the latest research regarding potential contributors to and underpinning mechanisms of this relationship.
Asimina I. Karampela, Maralyn Druce
wiley   +1 more source