Results 191 to 200 of about 5,539 (231)
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Neurological syndromes occurring in patients receiving synthetic steroids (oral contraceptives)
Neurology, 1966Case studies of 34 women with neurological syndromes associated with oral contraceptive use are discussed with a view to identifying contraindications of progestational steroid use. The patients were classified by occlusive cerebral arterial disease (5 patients) cortical vein thrombosis (1 patient) and vascular headaches (28 patients).
S, Shafey, P, Scheinberg
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The estrogenic activity of synthetic progestins used in oral contraceptives
Cancer, 1993AbstractBackground. Oral contraceptives (OC) contain an orally active estrogen in combination with an orally active synthetic progestin derived from 19‐nortestosterone. OC have had an enormous positive impact on public health for the past three decades, and in the main, there has been a remarkably low incidence of troublesome side effects.
V C, Jordan +3 more
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A Synthetic Steroid (R2323) as a Once-A-Week Oral Contraceptive
Fertility and Sterility, 1979Five milligrams of the steroid R2323 (13 beta-ethyl-17 alpha-ethynyl-17-hydroxygona-4,9,11-trien-3-one (R2323) were administered orally once weekly to 28 subjects for a total of 138 treatment cycles. No pregnancies occurred. The predominant side effects were irregular vaginal bleeding, headache, weight gain, and acne.
S S, David +3 more
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The metabolism of synthetic estrogens in non-users and users of oral contraceptives
Steroids, 1975Using both pulse injections and constant infusions of 3-H-mestranol (3H-ME) (1) and 3-H-ethinyl estradiol (3H-EE) we have studied the metabolism of these compounds in non-users and users of oral contraceptives. Following pulse injection of 3-H-ME the disappearance of radioactivity could be described as a function which was the sum of two exponentials ...
C, Longcope, K I, Williams
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Teratology, 1983
AbstractThirty timed‐mated pregnant rhesus monkeys received Norlestrin (Norethindrone acetate, 2.5 mg, and ethinyl estradiol, 0.05 mg pertablet, Parke‐Davis) orally at four different dose levels. The dose levels were 5, 10, 25 and 50 mg/day/monkey and the doses were administered during early (days 21–35), late (days 33–46), and throughout (days 21–46 ...
S, Prahalada, A G, Hendrickx
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AbstractThirty timed‐mated pregnant rhesus monkeys received Norlestrin (Norethindrone acetate, 2.5 mg, and ethinyl estradiol, 0.05 mg pertablet, Parke‐Davis) orally at four different dose levels. The dose levels were 5, 10, 25 and 50 mg/day/monkey and the doses were administered during early (days 21–35), late (days 33–46), and throughout (days 21–46 ...
S, Prahalada, A G, Hendrickx
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Contraception, 1977
Abstract The metabolic fate of isotopically labelled ethynylestradiol (EE) and its 3-methyl ether, mestranol (MEE), was investigated in three baboons who were receiving a norethindrone-mestranol combination oral contraceptive (C.O.C.) and the results compared to those previously obtained from the same baboons before receiving the C.O.C.
B D, Kulkarni, T D, Avila, J A, O'Leary
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Abstract The metabolic fate of isotopically labelled ethynylestradiol (EE) and its 3-methyl ether, mestranol (MEE), was investigated in three baboons who were receiving a norethindrone-mestranol combination oral contraceptive (C.O.C.) and the results compared to those previously obtained from the same baboons before receiving the C.O.C.
B D, Kulkarni, T D, Avila, J A, O'Leary
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Science of The Total Environment, 2011
Synthetic oral contraceptives (SOCs) are a group of compounds with progestagenic and/or androgenic activities, with some also possessing estrogenic activities. Recent research has documented that some of these emerging contaminants have adverse effects on aquatic organisms at very low concentrations.
Ze-hua, Liu +3 more
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Synthetic oral contraceptives (SOCs) are a group of compounds with progestagenic and/or androgenic activities, with some also possessing estrogenic activities. Recent research has documented that some of these emerging contaminants have adverse effects on aquatic organisms at very low concentrations.
Ze-hua, Liu +3 more
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Contraception, 1978
Two combined oral contraceptives, one containing ethinyl estradiol and the other micronized estradiol and estriol, were compared by measuring a variety of endocrine and renal parameters over nine months. Significant changes were observed in plasma renin activity (P.R.A.) on the synthetic estrogen.
D M, Saunders, B, Shuter, R P, Shearman
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Two combined oral contraceptives, one containing ethinyl estradiol and the other micronized estradiol and estriol, were compared by measuring a variety of endocrine and renal parameters over nine months. Significant changes were observed in plasma renin activity (P.R.A.) on the synthetic estrogen.
D M, Saunders, B, Shuter, R P, Shearman
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Acta Endocrinologica, 1978
ABSTRACT Increases in serum triglycerides, cholesterol and pre-β- and β-lipoproteins have been considered as significant pathogenic factors regarding the possible thrombotic side-effect of treatment with oral contraceptives of the combined type containing synthetic oestrogen.
E. Bostofte +4 more
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ABSTRACT Increases in serum triglycerides, cholesterol and pre-β- and β-lipoproteins have been considered as significant pathogenic factors regarding the possible thrombotic side-effect of treatment with oral contraceptives of the combined type containing synthetic oestrogen.
E. Bostofte +4 more
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