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Mastigophora and Rhizopoda found in saline lakes Weissovo and Repnoie (near Slaviansk). Selected passages describing Ochromonas species and Pedinella. [Translation of: Trudy Obshch.Ispyt.Prir.imp.khar'kov.Univ. 21 119-140, 1888] [PDF]

open access: yes, 1888
This translation includes selected passages of a longer paper on Mastigophora and Rhizopoda found in saline lakes Weissovo and Repnoie. The translation focuses on describing taxonomy and morphology of Ochromonas species and Pedinella.
Vysotskii, A. V.
core  

Integral membrane pyrophosphatases : A novel drug target for human pathogens? [PDF]

open access: yes, 2016
Membrane-integral pyrophosphatases (mPPases) are found in several human pathogens, including Plasmodium species, the protozoan parasites that cause malaria.
Adrian Goldman   +4 more
core   +3 more sources

High‐throughput screening identifies bazedoxifene as a potential therapeutic for dysferlin‐deficient limb girdle muscular dystrophy

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 13, Page 2930-2949, July 2025.
Abstract Background and Purpose Limb‐girdle muscular dystrophy R2 (LGMD R2) is a rare genetic disorder characterised by progressive weakness and wasting of proximal muscles. LGMD R2 is caused by the loss of function of dysferlin, a transmembrane protein crucial for plasma membrane repair in skeletal muscles.
Celine Bruge   +10 more
wiley   +1 more source

Mitochondria‐Homing Drug Mitochonic Acid 5 Improves Barth Syndrome Myopathy in a Human‐Induced Pluripotent Stem Cell Model and Barth Syndrome Drosophila Model

open access: yesThe FASEB Journal, Volume 39, Issue 12, 30 June 2025.
Barth syndrome (BTHS) is a rare disease caused by mutations in the tafazzin gene that affects the heart and muscles, but till date, no clinically effective drugs. Using Barth syndrome myopathy in human‐ iPS‐derived disease cells and Drosophila melanogaster model, a new mitochondria‐homing drug MA‐5, improves BTHS dysfunction and may serve as a new ...
Yoshiyasu Tongu   +29 more
wiley   +1 more source

mSphere of Influence: Compartmentalized cAMP signals in American trypanosomes

open access: yesmSphere
Noelia Lander works on cell signaling in American trypanosomes and studies the role of cyclic adenosine monophosphate (cAMP) microdomains in environmental sensing and differentiation. In this mSphere of Influence, Dr.
Noelia Lander
doaj   +1 more source

Trypanosomatid Aquaporins: Roles in Physiology and Drug Response [PDF]

open access: yes, 2013
In the class Kinetoplastida, we find an order of parasitic protozoans classified as Trypanosomatids. Three major pathogens form part of this order, Trypanosoma cruzi, Trypanosoma brucei, and Leishmania, which are responsible for disease and fatalities in
Mandal, Goutam   +3 more
core   +1 more source

Whole cell reconstructions of Leishmania mexicana through the cell cycle.

open access: yesPLoS Pathogens
The unicellular parasite Leishmania has a precisely defined cell architecture that is inherited by each subsequent generation, requiring a highly coordinated pattern of duplication and segregation of organelles and cytoskeletal structures. A framework of
Molly Hair   +7 more
doaj   +1 more source

Shedding light on the polyphyletic behavior of the genus Sterkiella: The importance of ontogenetic and molecular phylogenetic approaches [PDF]

open access: yes, 2018
Present study, investigates a poorly known species of the genus Sterkiella, i.e., S. tricirrata, based on two populations isolated from soil samples collected from the Colfiorito Regional Park, Umbria Region, Italy and from the Silent Valley National ...
Bharti, Daizy   +4 more
core   +5 more sources

Coral Disease and Health Workshop: Coral Histopathology II [PDF]

open access: yes, 2007
The health and continued existence of coral reef ecosystems are threatened by an increasing array of environmental and anthropogenic impacts. Coral disease is one of the prominent causes of increased mortality among reefs globally, particularly in the ...
Bochsler, V. S.   +14 more
core  

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