Results 71 to 80 of about 199,024 (258)
Contribution of microscopy for understanding the mechanism of action against trypanosomatids [PDF]
Transmission electron microscopy (TEM) has proved to be a useful tool to study the ultrastructural alterations and the target organelles of new antitrypanosomatid drugs.
A Martinez-Palomo+90 more
core +1 more source
Iron, zinc, and copper play fundamental roles in eucaryotes and procaryotes, and their bioavailability regulates host-pathogen interactions. For intracellular pathogens, the source of metals is the cytoplasm of the host, which in turn manipulates ...
Simona Buracco+4 more
doaj +1 more source
Contractile units in disordered actomyosin bundles arise from F-actin buckling [PDF]
Bundles of filaments and motors are central to contractility in cells. The classic example is striated muscle, where actomyosin contractility is mediated by highly organized sarcomeres which act as fundamental contractile units. However, many contractile bundles in vivo and in vitro lack sarcomeric organization.
arxiv +1 more source
Resolving the homology-function relationship through comparative genomics of membrane-trafficking machinery and parasite cell biology [PDF]
With advances in DNA sequencing technology, it is increasingly common and tractable to informatically look for genes of interest in the genomic databases of parasitic organisms and infer cellular states.
Aaron P. Turkewitz+210 more
core +2 more sources
Background Among Oligohymenophorea (Ciliophora, Alveolata) the subclass Peniculia stands as one of the most well-known groups. Frontonia is the largest genus of Peniculia, and its representatives are spread in any type of water bodies as well as in soil.
Valentina Serra+6 more
doaj +1 more source
Copine A Interacts with Actin Filaments and Plays a Role in Chemotaxis and Adhesion
Copines make up a family of calcium-dependent, phospholipid-binding proteins found in numerous eukaryotic organisms. Copine proteins consist of two C2 domains at the N-terminus followed by an A domain similar to the von Willebrand A domain found in ...
Matthew J. Buccilli+10 more
doaj +1 more source
Background Nitrogen (N) starvation in algae induces a variety of structural and metabolic changes including accumulation of triacylglycerol (TAG). Given the promising prospect of using algae as feedstock for biofuel production, accumulation of TAG upon N
Feifei Xu, Junmin Pan
doaj +1 more source
Evidence for Extracellular ATP as a Stress Signal in a Single-Celled Organism [PDF]
ATP is omnipresent in biology and acts as an extracellular signaling molecule in mammals. Information regarding the signaling function of extracellular ATP in single-celled eukaryotes is lacking.
Fountain, Samuel+1 more
core +2 more sources
During an ecological study of the epibiotic relationship between ciliate protists and Pomacea figulina (Spix, 1827) (Gastropoda, Ampullariidae), originating from an urban stream in southeast Brazil, a high infestation by the peritrich ciliate Carchesium ...
Roberto Júnio P. Dias+4 more
doaj +1 more source
Rab GTPases are essential regulators of many cellular processes and play an important role in downstream signaling vital to proper cell function. We sought to elucidate the role of novel D. discoideum GTPase RabS.
Azure Yarbrough+4 more
doaj +1 more source