Results 71 to 80 of about 306,616 (240)

Hydro-osmotic instabilities in active membrane tubes [PDF]

, 2018
We study a membrane tube with unidirectional ion pumps driving an osmotic pressure difference. A pressure driven peristaltic instability is identified, qualitatively distinct from similar tension-driven Rayleigh type instabilities on membrane tubes.
Al-Izzi, Sami C., Rowlands, George, Sens, Pierre, Turner, Matthew S.   +3 more
core   +2 more sources

A novel transgenic reporter of extracellular acidification in zebrafish elucidates skeletal muscle T‐tubule pH regulation

Developmental Dynamics, Volume 254, Issue 9, Page 1068-1079, September 2025.
Abstract Disruption of extracellular pH and proton‐sensing can profoundly impact cellular and protein functions, leading to developmental defects. To visualize changes in extracellular pH in the developing embryo, we generated a zebrafish transgenic line that ubiquitously expresses the ratiometric pH‐sensitive fluorescent protein pHluorin2, tethered to
Leif R. Neitzel, Maya Silver, Aaron H. Wasserman, Samantha Rea, Charles C. Hong, Charles H. Williams   +5 more
wiley   +1 more source

TcCARP3 modulates compartmentalized cAMP signals involved in osmoregulation, infection of mammalian cells, and colonization of the triatomine vector in the human pathogen Trypanosoma cruzi

mBio
Trypanosoma cruzi is the causative agent of Chagas disease, a zoonotic infectious disease considered a leading cause of cardiomyopathy, disability, and premature death in the Americas.
Joshua Carlson, Milad Ahmed, Riley Hunter, Syeda Farjana Hoque, Joshua B. Benoit, Miguel A. Chiurillo, Noelia Lander   +6 more
doaj   +1 more source

Nramp1 and NrampB Contribute to Resistance against Francisella in Dictyostelium

Frontiers in Cellular and Infection Microbiology, 2017
The Francisella genus comprises highly pathogenic bacteria that can cause fatal disease in their vertebrate and invertebrate hosts including humans. In general, Francisella growth depends on iron availability, hence, iron homeostasis must be tightly ...
Yannick Brenz, Denise Ohnezeit, Hanne C. Winther-Larsen, Monica Hagedorn   +3 more
doaj   +1 more source

Cell stress by phosphate of two protozoa tetrahymena thermophila and tetrahymena pyriformis [PDF]

, 2017
Phosphorus is one of the bioelements most needed as a compound cell by living organisms. Phosphorus is involved in several pathologies: in human with bone and kidney diseases, in mammals with metabolism disorder (glucose, insulin···), in microorganisms ...
Elkhalfi, Bouchra, Papa Daouda, Mar, Pérez Castiñeira, José Román, Serrano Delgado, Aurelio, Soukri, Abdelaziz   +4 more
core   +1 more source

Complex sphingolipid profiling and identification of an inositol-phosphorylceramide synthase in Dictyostelium discoideum

iScience
Summary: Dictyostelium discoideum is a professional phagocyte frequently used to study cellular processes underlying the recognition, engulfment, and infection course of microbial pathogens.
Stevanus A. Listian, Anna-Carina Mazur, Matthijs Kol, Edwin Ufelmann, Sebastian Eising, Florian Fröhlich, Stefan Walter, Joost C.M. Holthuis, Caroline Barisch   +8 more
doaj   +1 more source

Iron metabolism and resistance to infection by invasive bacteria in the social amoeba Dictyostelium discoideum

Frontiers in Cellular and Infection Microbiology, 2013
Dictyostelium cells are forest soil amoebae, which feed on bacteria and proliferate as solitary cells until bacteria are consumed. Starvation triggers a change in life style, forcing cells to gather into aggregates to form multicellular organisms ...
Salvatore eBozzaro, Simona eBuracco, Barbara ePeracino   +2 more
doaj   +1 more source

Heavy Metals Toxicity: Mechanism, Health Effects, and Therapeutic Interventions

MedComm, Volume 6, Issue 9, September 2025.
Heavy metals exert a wide range of effects at the cellular, molecular, and genetic levels, leading to neurological damage, renal dysfunction, cardiovascular disease, reproductive developmental abnormality, immune system abnormality, and increased risk of cancer by interfering with biomolecule function, signaling pathways, inducing oxidative stress, and
Yu‐feng Cheng, Yu‐jia Zhao, Ce Chen, Feng Zhang   +3 more
wiley   +1 more source

Metabolic Profile Associated With Encystation in Acanthamoeba

Journal of Eukaryotic Microbiology, Volume 72, Issue 5, September/October 2025.
ABSTRACT The genus Acanthamoeba includes widespread protozoa that can cause severe infections in humans. Their ability to form resistant cysts within infected tissues complicates treatment, making it essential to understand the encystation process for developing effective therapeutic strategies.
Cecília Cirelli, Isabela Aurora Rodrigues, Jéssica Gardone Vitório, Filipe Fideles Duarte‐Andrade, Gisele André Baptista Canuto, Leiliane Coelho André, Juliano Simões de Toledo, Ana Paula Fernandes, Adriana Oliveira Costa   +8 more
wiley   +1 more source

The behaviour of contractile vacuole complexes of cryptophycean flagellates [PDF]

British Phycological Journal, 1981
The behaviour of contractile vacuole complexes of representatives of the Cryptophycean genera Chilomonas, Cryptomonas, Cyathomonas and Rhodomonas is described using light and electron microscopy. The contractile vacuole occupies a fixed position in the cell, lying adjacent to the flagellar pocket/groove.
Klaus Hausmann, David J. Patterson
openaire   +2 more sources