Results 81 to 90 of about 316,695 (204)

Complex sphingolipid profiling and identification of an inositol-phosphorylceramide synthase in Dictyostelium discoideum

iScience
Summary: Dictyostelium discoideum is a professional phagocyte frequently used to study cellular processes underlying the recognition, engulfment, and infection course of microbial pathogens.
Stevanus A. Listian, Anna-Carina Mazur, Matthijs Kol, Edwin Ufelmann, Sebastian Eising, Florian Fröhlich, Stefan Walter, Joost C.M. Holthuis, Caroline Barisch   +8 more
doaj   +1 more source

Iron metabolism and resistance to infection by invasive bacteria in the social amoeba Dictyostelium discoideum

Frontiers in Cellular and Infection Microbiology, 2013
Dictyostelium cells are forest soil amoebae, which feed on bacteria and proliferate as solitary cells until bacteria are consumed. Starvation triggers a change in life style, forcing cells to gather into aggregates to form multicellular organisms ...
Salvatore eBozzaro, Simona eBuracco, Barbara ePeracino   +2 more
doaj   +1 more source

Inhaled Halogen‐Induced Oxidative Renal Damage and Dysfunction: A Lung Heart Kidney Axis

Comprehensive Physiology, Volume 16, Issue 1, February 2026.
Mechanisms of lung‐heart‐kidney interaction in inducing organ injury after chemical inhalation. Acute exposure to halogen gases causes extensive lung injury and acute cardiac damage leading to fatalities. Formation of highly reactive halogenated molecules in the pulmonary bed and their circulation resulting in oxidative stress and inflammation was ...
Juan Xavier Masjoan Juncos, Ahmed Zaky, Wesam Nasser, Amber J. Johns, Iram Zafar, Gajanan R. Jadhav, Jeremy B. Foote, Aftab Ahmad, Anupam Agarwal, Shama Ahmad   +9 more
wiley   +1 more source

Reference Methods for Measuring Skeletal Muscle Mass: A Critical Perspective

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Skeletal muscle (SM) is an integral organ component in the pathophysiology of many acute and chronic diseases. But is there a ‘gold’ standard or accepted reference method for quantifying the amount and composition of human SM mass? Exploring that question led us to recognize the existence of a SM measurement paradigm that divides methods into ...
Steven B. Heymsfield, Houchun H. Hu, Edvin Johanssen, Sophia Ramirez, Gabriela de Oliveira Lemos, Maria Cristina Gonzalez, Carla M. Prado, Jonathan P. Bennett   +7 more
wiley   +1 more source

Mechanosensing in Dendritic Cells

Immunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Since their discovery, dendritic cells have been recognized for their unusual capacity to sense and respond to physical stimuli within their environment. However, it took nearly two decades—and the advent of mechanobiology—to elucidate the underlying mechanisms and functional implications of this mechanical hypersensitivity. In this review, we
Vincent Calmettes, Melissa A. Quintanilla, Livia Lacerda Mariano, Matthieu Piel, Hélène D. Moreau, Ana‐Maria Lennon‐Duménil   +5 more
wiley   +1 more source

Elastic Energy Storage in Biological Materials: Internal Stresses and Their Functionality

Advanced Materials, Volume 37, Issue 51, December 23, 2025.
Harnessing and storing internally generated elastic energy is a clever strategy by biological materials to perform functions like shape transformation, movement, and predation. This review explores how biological systems manipulate mechanisms like atomic or protein integration into minerals, protein conformational shifts, phase transitions, and osmotic
Shahrouz Amini, Paul Zaslansky, Boaz Pokroy, Peter Fratzl   +3 more
wiley   +1 more source

Astragaloside IV alleviates hypoxic pulmonary hypertension by inhibiting RELM‐β to reduce PINK1/Parkin‐mediated mitophagy in pulmonary artery smooth muscle cells (PASMCs)

British Journal of Pharmacology, Volume 182, Issue 24, Page 5933-5952, December 2025.
Background and Purpose Hypoxic pulmonary hypertension (HPH) is a chronic disorder marked by irreversible pulmonary vascular remodelling (PVR) and pulmonary artery smooth muscle cell (PASMC) dysfunction. Astragaloside IV (AS‐IV), a natural saponin from Astragalus, shows potential in HPH management. This study explores AS‐IV's protective effect on PVR in
Rongzhen Ding, Haiping Xie, Shuliu Sang, Li Qin, Yinhui Sun, Chao Zhang, Jian Yi, Hui Liu, Jianmin Fan, Guoran Peng, BeiBei Cheng, Lan Song, Aiguo Dai   +12 more
wiley   +1 more source

Shining a Light on Skeletal Muscle Regeneration: Red Photobiomodulation Boosts Myoblast Differentiation In Vitro

The FASEB Journal, Volume 39, Issue 21, 15 November 2025.
Red (635 ± 10 nm) photobiomodulation (PBM) with an energy density of 4 J/cm2 enhances myogenic differentiation of murine skeletal myoblasts by promoting F‐actin assembly, modulating bioelectrical plasmamembrane properties, and increasing the expression of myogenic markers, mitochondrial biogenesis and activity, and secretion of promyogenic ...
Martina Parigi, Alessia Tani, Francesco Palmieri, Rachele Garella, Aurora Longhin, Gabriella Teti, Daniele Nosi, Daniele Guasti, Caterina Licini, Alessandra La Contana, Mirella Falconi, Monica Mattioli Belmonte, Roberta Squecco, Flaminia Chellini, Chiara Sassoli   +14 more
wiley   +1 more source

Effects of TcFLA‐1BP and TcGP72 Deletion on the Infectivity and Survival of Trypanosoma cruzi in Cell Cultures

Cell Biology International, Volume 49, Issue 11, Page 1395-1410, November 2025.
ABSTRACT Chagas disease, caused by the protozoan Trypanosoma cruzi, is a neglected tropical disease with limited treatment options and no available vaccine. Understanding the role of proteins in the parasite's biological cycle is critical for advancing vaccine development and optimizing therapies.
Normanda Souza‐Melo, Giovanna Henriques de Souza, Wanderley de Souza   +2 more
wiley   +1 more source

Shedding light on the polyphyletic behavior of the genus Sterkiella: The importance of ontogenetic and molecular phylogenetic approaches [PDF]

, 2018
Present study, investigates a poorly known species of the genus Sterkiella, i.e., S. tricirrata, based on two populations isolated from soil samples collected from the Colfiorito Regional Park, Umbria Region, Italy and from the Silent Valley National ...
Bharti, Daizy, Kamra, Komal, Kumar, Santosh, LA TERZA, Antonietta, Varatharajan, Govindhasamay R.   +4 more
core   +5 more sources