Results 121 to 130 of about 254,999 (359)

Coupling biochemistry and mechanics in cell adhesion: a model for inhomogeneous stress fiber contraction

open access: yes, 2007
Biochemistry and mechanics are closely coupled in cell adhesion. At sites of cell-matrix adhesion, mechanical force triggers signaling through the Rho-pathway, which leads to structural reinforcement and increased contractility in the actin cytoskeleton.
Achim Besser   +14 more
core   +1 more source

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández   +4 more
wiley   +1 more source

Active contractility in actomyosin networks

open access: yes, 2012
Contractile forces are essential for many developmental processes involving cell shape change and tissue deformation. Recent experiments on reconstituted actomyosin networks, the major component of the contractile machinery, have shown that active ...
Backouche   +22 more
core   +1 more source

Altering sphingolipid composition with aging induces contractile dysfunction of gastric smooth muscle viaKCa1.1 upregulation [PDF]

open access: gold, 2015
Shinkyu Choi   +9 more
openalex   +1 more source

Self‐Assembling Peptide Hydrogels Support Stromal Vascular Fraction Viability to Promote In Vivo Nerve Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
Stromal vascular fraction (SVF) may enhance nerve repair, especially when delivered in a self‐assembling peptide hydrogel (SAPH). In vitro, softer SAPH increased neuronal explant outgrowth and supported greater SVF viability and proliferation. In a rat sciatic defect, SVF in an optimized SAPH produced motor and sensory recovery equivalent to autograft ...
Liam A. McMorrow   +6 more
wiley   +1 more source

LYMPHATIC CONTRACTILITY [PDF]

open access: yesJournal of Experimental Medicine, 1949
The most peripheral lymphatic vessels of rats, mice, and guinea pigs were found to possess a spontaneous intermittent contractility. (a) The rate of contraction was shown to be directly proportional to the rate of formation of lymph and contractions were apparently initiated by an increase in intraluminal pressure.
openaire   +1 more source

Collective dynamics of actomyosin cortex endow cells with intrinsic mechanosensing properties

open access: yes, 2015
Living cells adapt and respond actively to the mechanical properties of their environment. In addition to biochemical mechanotransduction, evidence exists for a myosin-dependent, purely mechanical sensitivity to the stiffness of the surroundings at the ...
Asnacios, Atef   +5 more
core   +3 more sources

Mesenchymal Stem Cell‐Derived Apoptotic Micro‐Vesicles Repaired Sciatic Nerve Defect by Regulating Early Inflammatory Microenvironment and Promoting Angiogenesis

open access: yesAdvanced Healthcare Materials, EarlyView.
HUCMSC‐Apo‐mvs enhance peripheral nerve repair by modulating the inflammatory microenvironment (IME), primarily through coordinated actions on three functional cells. They recruit macrophages and promote their polarization from pro‐inflammatory M1 to anti‐inflammatory M2 phenotypes, increasing secretion of IL‐10 and VEGF.
Haolin Liu   +21 more
wiley   +1 more source

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