Results 211 to 220 of about 248,671 (308)

Ultra‐High Friction and Adhesion in Hydrogel Layer Driven by Wet‐to‐Dry Transition Dynamics

open access: yesAdvanced Science, EarlyView.
This work reveals a critical wet‐to‐dry transition in polyacrylamide hydrogel layers that induces volumetric shrinkage, resulting in enhanced interfacial contact and dramatically increased friction and adhesion. Leveraging this transition enables strong, reversible gripping on diverse surfaces, offering new insights for hydrogel‐based gripping ...
Chenxu Liu   +11 more
wiley   +1 more source

LncRNA THUMPD3‐AS1 Regulates Behavioral and Synaptic Structural Abnormalities in Schizophrenia via miR‐485‐5p and ARHGAP8

open access: yesAdvanced Science, EarlyView.
Schizophrenia (SCZ) is linked to synaptic structural deficits driven by dysregulated noncoding RNAs. Using the novel ceRNAxis pipeline, THUMPD3‐AS1/miR‐485‐5p/ARHGAP8 is identified as a key regulator of actin cytoskeletal remodeling through noncanonical RhoB/C‐ROCK2 signaling. Modulating this axis ameliorates SCZ‐like phenotypes in mice and aligns with
Xiaojuan Gong   +9 more
wiley   +1 more source

Decoding uterine (dys)function in fibroids through multimodal assessment of functional determinants: a systematic review and meta-analysis. [PDF]

open access: yesHum Reprod Open
Salmeri N   +7 more
europepmc   +1 more source

Chronic clenbuterol treatment compromises force production without directly altering skeletal muscle contractile machinery

open access: green, 2015
Guillaume Py   +12 more
openalex   +2 more sources

SpaBatch: Deep Learning‐Based Cross‐Slice Integration and 3D Spatial Domain Identification in Spatial Transcriptomics

open access: yesAdvanced Science, EarlyView.
SpaBatch is an end‐to‐end multi‐slice spatial transcriptomics data integration framework. It simultaneously performs embedding learning, spatial feature denoising and reconstruction, batch effect correction, and spatial domain optimization, effectively correcting batch effects and achieving accurate 3D spatial domain identification.
Jinyun Niu   +5 more
wiley   +1 more source

Mechanical Cell Reprogramming on Tissue-Mimicking Hydrogels for Cancer Cell Transdifferentiation. [PDF]

open access: yesResearch (Wash D C)
Ren X   +13 more
europepmc   +1 more source

Contractile forces in platelet aggregates under microfluidic shear gradients reflect platelet inhibition and bleeding risk [PDF]

open access: gold, 2019
Lucas H. Ting   +10 more
openalex   +1 more source

Tumor‐Tissue Boundaries as Instructive Interfaces in Breast Cancer Cell Invasion

open access: yesAdvanced Science, EarlyView.
Tumor‐tissue boundaries reprogram metastatic breast cancer cells, enhancing invasiveness through an instructive, not permissive, mechanism. Using a 3D collagen I‐based tumor‐tissue interface model, single‐cell analysis, and simulations, this study shows that all cells can transmigrate without selective filtering, highlighting a targetable process in ...
Cornelia Clemens   +6 more
wiley   +1 more source

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