Results 61 to 70 of about 14,205 (282)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
On Fixed Points of α-ψ-Contractive Multivalued Mappings in Cone Metric Spaces
Abstract and Applied Analysis, 2013 We define the notion of α*-ψ-contractive mappings for cone metric space and obtain fixed points of multivalued mappings in connection with Hausdorff distance function for closed bounded subsets of cone metric spaces.
Marwan Amin Kutbi +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Picard $ S $-type semi implicit mid-point method for fixed point approximation with applications
AIMS MathematicsIn this article, our goal is to propose and design a hybrid Picard $ S $-type semi-implicit mid-point method to approximate the fixed point of a contractive-like mapping.
Doaa Filali +3 more
doaj +1 more source
Fixed point theorems for compatible multi-valued and single-valued mappings
International Journal of Mathematics and Mathematical Sciences, 1989 The notion of compatibility for point-to-point mappings recently defined by Jungck is generalized to include multi-valued mappings. This idea is used to establish a fixed point theorem for a generalized contractive multi-valued mapping and a single ...
Hideaki Kaneko, Salvatore Sessa
doaj +1 more source
An Approach of Lebesgue Integral in Fuzzy Cone Metric Spaces via Unique Coupled Fixed Point Theorems
Journal of Function Spaces, 2021 In the theory of fuzzy fixed point, many authors have been proved different contractive type fixed point results with different types of applications. In this paper, we establish some new fuzzy cone contractive type unique coupled fixed point theorems ...
Muhammad Talha Waheed +4 more
doaj +1 more source
The Monotone Contraction Mapping Theorem [PDF]
Journal of Mathematics, 2020 In this paper, the fixed-point theorem for monotone contraction mappings in the setting of a uniformly convex smooth Banach space is studied. This paper provides a version of the Banach fixed-point theorem in a complete metric space.
openaire +3 more sources
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
, 2014 Local iterated function systems are an important generalisation of the standard (global) iterated function systems (IFSs). For a particular class of mappings, their fixed points are the graphs of local fractal functions and these functions themselves are
Barnsley, Michael F. +2 more
core
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source