Results 111 to 120 of about 4,671,855 (301)

Uptake of Gadolinium-Based Contrast Agents by Blood Cells During Contrast-Enhanced MRI Examination. [PDF]

OBJECTIVES Gadolinium-based contrast agents (GBCAs) are routinely used in magnetic resonance imaging (MRI) examinations. However, there is limited knowledge about the interaction with and distribution of the drug in human cells. This lack of knowledge
Broekmann, Peter, von Tengg-Kobligk, Hendrik, Hofmann, Lukas, Heverhagen, Johannes Thomas, Kempf, Christoph, Parakkattel, Dixy, Ruprecht, Nico, Lüdi, Nicola   +7 more
core   +2 more sources

Modeling Progressive Brain Volume Losses in Chronic Moderate Severe Traumatic Brain Injury: Extensive, but Attenuating

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progressive brain atrophy has now been widely observed in the chronic stages of moderate–severe traumatic brain injury (msTBI), but there is only coarse information regarding its prevalence and magnitude, and whether rate of atrophy accelerates or attenuates across time. We examined these questions in a Canadian inception cohort from
Robin E. A. Green, Brenda Colella, Alana Changoor, David J. Mikulis, Adrienne Li, Kadeen Johns, Georges A. Monette   +6 more
wiley   +1 more source

Semi-parametric analysis of dynamic contrast-enhanced MRI using bayesian P-splines

, 2006
Current approaches to quantitative analysis of DCE-MRI with non-linear models involve the convolution of an arterial input function (AIF) with the contrast agent concentration at a voxel or regional level.
Whitcher, B., Yang, G.-Z., Schmid, V.J.
core   +1 more source

Metabolic and Fluid Biomarkers Support Microglia Activation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis is an incurable neurodegenerative disease involving motor neuron degeneration and metabolic and immune dysfunction. We combined clinical data, cerebrospinal fluid biomarkers and fluorodeoxyglucose positron emission tomography with magnetic resonance imaging to investigate the role of reactive microglia in disease ...
Matteo Zanovello, Francesca Serani, Alen Bebeti, Federica Paredi, Giulia Quadrio, Andrea Fortuna, Giacomo Maria Minicuci, Elena Pegoraro, Annachiara Cagnin, Diego Cecchin, Gianni Sorarù   +10 more
wiley   +1 more source

Magnetic resonance imaging in the evaluation of different compression locations in patients with cervical spondylotic radiculopathy

Journal of Orthopaedic Surgery and Research
Objective Studies showed that T2-weighted turbo spin-echo SPACE (T2-SPACE) could be superior to conventional two-dimensional magnetic resonance imaging (2D MRI) to detect the locations of nerve root compression.
Yu Wang, Xiaolong Chen, Xiang-yu Li, Dongfan Wang, Dongdong Rong, Zheng Sun, Jie Lu, Shibao Lu   +7 more
doaj   +1 more source

Periodic table screening for enhanced positive contrast in MRI and in vivo uptake in glioblastoma [PDF]

The quest for nanomaterial-based imaging probes that can provide positive contrast in MRI is fueled by the necessity of developing novel diagnostic applications with potential for clinical translation that current gold standard probes cannot provide ...
Jesús, Ruiz-Cabello, Lydia, Martínez-Parra, Fernando, Herranz, Carlos, Díaz-Ufano, M. Puerto, Morales, Nuria, Arias-Ramos, Pilar, López-Larrubia, Lucía, Gutierrez, Aitor, Herraiz, Jesús, Mejías   +9 more
core   +2 more sources

Diffuse MRI Edema Predicts Relapse in Cerebral Amyloid Angiopathy–Related Inflammation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify MRI predictors of relapse and quantify relapse and mortality risk in cerebral amyloid angiopathy–related inflammation (CAA‐RI). A secondary objective was to assess the association between mycophenolate mofetil use and relapse risk. Methods We performed a retrospective cohort study of 36 patients with CAA‐RI treated at the
G. Abbas Kharal, Gowtham Yerneni, Kim J. Griffin, Nicolas Thompson, Ken Uchino, Irene Katzan, Dolora Wisco, Abeer Farrag, Jayashree Sundarajan, Andrew Russman, M. Shazam Hussain   +10 more
wiley   +1 more source

Detection of a contralateral breast malignancy using contrast-enhanced mammography (CEM) overlooked by initial MRI scan

Radiology Case Reports
Contrast-enhanced mammography (CEM) has emerged as a promising technology in the field of breast imaging, experiencing growing acceptance. However, the comparative evaluation of its diagnostic accuracy against MRI remains sparse, largely attributed to ...
Roya Faghani, MD, Sahar Darabi Monadi, MD, Vasiliki Papalouka, MD, Tamara Suaris, MD   +3 more
doaj   +1 more source

Utility of the APE2 Score as a Diagnostic Tool for Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To retrospectively evaluate the diagnostic performance of the Antibody Prevalence in Epilepsy and Encephalopathy (APE2) score relative to clinician‐adjudicated autoimmune encephalitis (AE) and the Graus criteria in a tertiary neuroimmunology referral cohort, including antibody‐negative AE.
Bijoya Basu, Sophia F. Damman, Samhitha M. Rai, Hesham Abboud   +3 more
wiley   +1 more source

Association Between Neurofilament Light Chain and Real‐World Ambulatory Function in Progressive MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurofilament light chain (NfL) is a biomarker of neuroaxonal injury in multiple sclerosis (MS), yet associations with functional outcomes remain unclear. Longitudinal associations between serum NfL (sNfL) and daily step count (STEPS) from wearable devices were assessed in a large international progressive MS cohort.
Gabby B. Joseph, Megan McCune, Riley Bove, Ahmed Abdelhak, Bruce A. C. Cree, Valerie J. Block   +5 more
wiley   +1 more source