Results 201 to 210 of about 5,583,294 (267)

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Optimization of the Sequence of Computed Tomography Angiography and Perfusion in One-Stop-Shop CT Imaging for Acute Ischemic Stroke. [PDF]

Med Sci Monit
Gao B, Yuan J, Wang J, Lv X, Wang Y.
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Evaluation of deep-learning iterative reconstruction combined with high-frequency kernels in CT: a task-based image quality study. [PDF]

Eur Radiol Exp
Viry A, Monnin P, Pozzessere C, Racine D.   +3 more
europepmc   +1 more source

Computed Tomographic Findings and Clinical Manifestations of Acute Severe Hypersensitivity to a Non-Ionic Iodinated Contrast Agent in a Castrated Male Dog: A Case Report. [PDF]

Animals (Basel)
Chung M, Kwak J, Eom K, Kim J.
europepmc   +1 more source

Adrenocortical Carcinoma: An Exceptional Survival Span Across a Tailored Management. [PDF]

Diagnostics (Basel)
Carsote M, Sima OC, Costachescu M, Terzea D, Gheorghe AM, Dumitrascu A, Constantin TI, Nistor C, Dima A.   +8 more
europepmc   +1 more source

Association of the Triglyceride-Glucose Index with Contrast-Associated Acute Kidney Injury in Patients with Atherosclerotic Renal Artery Stenosis. [PDF]

J Cardiovasc Dev Dis
Celebi Coskun E, Kapsiz M.
europepmc   +1 more source