Results 71 to 80 of about 676,754 (296)

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Contrast Enhancement in 2D Nanomaterial SEM Images

Engineering Proceedings
Owing to their large size and flexibility, 2D nanostructures (e.g., graphene, graphene oxide, single-layer molybdenum disulfide, etc.) are technologically exploited in a supported form. Glass, silicon, and polymers are typical substrates.
Angela Longo, Mariano Palomba, Filippo Giubileo, Gianfranco Carotenuto   +3 more
doaj   +1 more source

Contrast Enhancement for Topographic Imaging in Confocal Laser Scanning Microscopy

Applied Sciences, 2019
The influence of the axial pinhole position in a confocal microscope in terms of the contrast of the image is analyzed. The pinhole displacement method is introduced which allows to increase the contrast for topographic imaging.
Lena Schnitzler, Markus Finkeldey, Martin R. Hofmann, Nils C. Gerhardt   +3 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Evaluatıon of contrast enhancement intensity, pattern, and kinetics of breast lesions on contrast-enhanced spectral mammography

The Egyptian Journal of Radiology and Nuclear Medicine
Background Contrast-enhanced spectral mammography (CESM) is a new and promising imaging modality that improves tumor visibility through tumor contrast enhancement caused by malignant neovascularization. Breast magnetic resonance imaging (MRI) is based on
Ayşe Füsun Bekirçavuşoğlu, Sibel Kul, Süleyman Bekirçavuşoğlu, Dilara Atasoy, Merve Erkan   +4 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Adaptive Contrast Enhancement With Lesion Focusing (ACELF)

IEEE Access
This study introduces an innovative image processing algorithm, namely Adaptive Contrast Enhancement with Lesion Focusing (ACELF), which is aimed at enhancing the visualization of brain lesions images.
Jinger Ang, Kok Swee Sim, Shing Chiang Tan, Chee Peng Lim   +3 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Automatic Contrast-Limited Adaptive Histogram Equalization With Dual Gamma Correction

IEEE Access, 2018
We propose automatic contrast-limited adaptive histogram equalization (CLAHE) for image contrast enhancement. We automatically set the clip point for CLAHE based on textureness of a block.
Yakun Chang, Cheolkon Jung, Peng Ke, Hyoseob Song, Jungmee Hwang   +4 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source