Results 121 to 130 of about 7,957,103 (318)
Intrusive origin of the Sudbury Igneous Complex: Structural and sedimentological evidence [PDF]
In recent years, many geoscientists have come to believe that the Sudbury event was exogenic rather than endogenic. Critical to a recent exogenic hypothesis is the impact melt origin of the Sudbury Igneous Complex (SIC).
Cowan, E. J., Schwerdtner, W. M.
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
PERTUMBUHAN DAN KETIMPANGAN (SUATU TINJAUAN HYPHOTHESIS KUZNET)
Jurnal Ekonomi Pembangunan, 2011 The impact of economic growth upon the poor in developing countries is complex and contentious. Does growth benefit in asociety all, and how does it affect inequality and vulnerability?
Emi Suwarni, Mardalena Mardalena
doaj +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Purchasing Power Parity Hypothesis in Developing Economies:Some Empirical Evidence from Sri Lanka [PDF]
Purchasing power parity (PPP) hypothesis has attracted a lot of attention from academics and policy-makers particularly, during the recent float. Most previous studies used data from the developed world.
Guneratne Banda Wickremasinghe
core +3 more sources
Linear Systems Analysis of Functional Magnetic Resonance Imaging in Human V1
Journal of Neuroscience, 1996 The linear transform model of functional magnetic resonance imaging (fMRI) hypothesizes that fMRI responses are proportional to local average neural activity averaged over a period of time.
G. Boynton +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Impact of Life History on Fear Memory and Extinction
Frontiers in Behavioral Neuroscience, 2016 Behavioral profiles are strongly shaped by an individual’s whole life experience. The accumulation of negative experiences over lifetime is thought to promote anxiety-like behavior in adulthood (‘allostatic load hypothesis’).
Jasmin Remmes +12 more
doaj +1 more source
Effect of contrast on the perception of direction of a moving pattern [PDF]
A series of experiments examining the effect of contrast on the perception of moving plaids was performed to test the hypothesis that the human visual system determines the direction of a moving plaid in a two-staged process: decomposition into component
Mulligan, J. B. +2 more
core +1 more source