Results 111 to 120 of about 3,408,895 (339)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Evaluation of visual acuity and contrast sensitivity in early cataract

مجله دانشگاه علوم پزشکی گرگان, 2021
Background and Objective: Age-related cataract is one of the most important causes of blindness. Early detection of cataracts can help alleviate the problems caused by this disease.
Monireh Mahjoob, Farkhonde Shahri
doaj  

Magnetometry with nitrogen-vacancy ensembles in diamond based on infrared absorption in a doubly resonant optical cavity

, 2013
We propose to use an optical cavity to enhance the sensitivity of magnetometers relying on the detection of the spin state of high-density nitrogen-vacancy ensembles in diamond using infrared optical absorption.
Acosta, Victor, Budker, Dmitry, Chipaux, Mayeul, Debuisschert, Thierry, Dumeige, Yannick, Jacques, Vincent, Jarmola, Andrey, Jensen, Kasper, Kehayias, Pauli, Roch, Jean-François, Treussart, François   +10 more
core   +3 more sources

Contrasting the modelled sensitivity of the Amundsen Sea Embayment ice streams [PDF]

, 2016
Isabel Nias, Stephen Cornford, A. J. Payne   +2 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Correlation between contrast sensitivity and higher-order aberration based on pupil diameter after cataract surgery

Clinical Ophthalmology, 2011
Takefumi Yamaguchi1,2, Kazuno Negishi1, Kazuhiko Ohnuma3, Kazuo Tsubota11Department of Ophthalmology, Keio University School of Medicine, Tokyo; 2Department of Ophthalmology, Ichikawa General Hospital, Tokyo Dental College, Chiba; 3Department of Medical ...
Yamaguchi T, Negishi K, Ohnuma K, Tsubota K   +3 more
doaj  

Electroretinography and contrast sensitivity, complementary translational biomarkers of sensory deficits in the visual system of individuals with fragile X syndrome [PDF]

, 2021
Olivier Perche, Fabien Lesne, Alain Patat, Susanne Raab, Roy E. Twyman, Robert H. Ring, Sylvain Briault   +6 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Effect of Fasting on Contrast Sensitivity in Healthy Males

Journal of Ophthalmic & Vision Research, 2019
Purpose: To evaluate the effect of fasting on contrast sensitivity (CS) in healthy male individuals during the month of Ramadan. Methods: This study included 45 healthy male individuals, aged between 20 and 40 years, working in the same environment.
Zarife Ekici Gok, Abuzer Gunduz, Cem Cankaya   +2 more
doaj   +1 more source

Analysis of dynamic system optimum and externalities with departure time choice [PDF]

, 2006
This paper aims to analyse the dynamic system optimal assignment with departure time choice, which is an important, yet underdeveloped area. The main contribution of this paper is the necessary conditions and the sensitivity analysis for dynamic system
Chow, A.H.F.
core