Results 121 to 130 of about 7,979,651 (342)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Adaptive shifts of spatiotemporal contrast sensitivity function: context adaptation vs. point adaptation

, 2014
Ambarish S. Pawar, Thomas D. Albright, Sergei Gepshtein   +2 more
openalex   +1 more source

Proposal of a Quality-Index or Metric for Soft Copy Display Systems: Contrast Sensitivity Study [PDF]

, 2003
Jihong Wang, Ken Compton, Qi Peng
openalex   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Sensibilidade ao contraste a grades senoidais de freqüências espaciais baixas em crianças

Estudos de Psicologia (Campinas)
O objetivo deste trabalho foi determinar a função de sensibilidade ao contraste para freqüências espaciais de 0,25; 0,5; 1,0 e 2,0 ciclos por grau em crianças de 4 a 13 anos.
Natanael Antonio dos Santos, Valtenice de Cássia Rodrigues de Matos França   +1 more
doaj   +1 more source

Quick contrast sensitivity assessment in primates using an exploratory search task

, 2019
Mariana M. B. Cardoso, Najib J. Majaj, Gerick M. Lee, Krysten Garcia, Lynne Kiorpes   +4 more
openalex   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Contrast sensitivity of insect motion detectors to natural images

, 2008
Andrew Straw, Tamath Rainsford, David C. O’Carroll   +2 more
openalex   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Contrast sensitivity and disability glare in patients with dry eye [PDF]

, 2006
María C. Puell, José M. Benítez‐del‐Castillo, J.M. Martínez-de-la-Casa, Celia Sánchez-Ramos Roda, Eva Aladro Vico, María Jesús Pérez‐Carrasco, Constanza Pedraza, Almudena Del‐Hierro   +7 more
openalex   +1 more source