Results 141 to 150 of about 7,979,651 (342)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Contrast Sensitivity Testing [PDF]

Ophthalmology, 1984
A, Atkin, I, Bodis-Wollner, M, Wolkstein, S, Podos   +3 more
openaire   +3 more sources

Senescence of spatial chromatic contrast sensitivity II Matching under natural viewing conditions

, 2005
Peter B. Delahunt, Katsunori Okajima, John S. Werner, Joseph L. Hardy   +3 more
openalex   +1 more source

Visual acuity and contrast sensitivity after posterior lamellar keratoplasty [PDF]

, 2011
Esben Nielsen, Jesper Hjortdal
openalex   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Association of Structural and Functional Measures With Contrast Sensitivity in Glaucoma.

American journal of ophthalmology-glaucoma, 2017
Nima Fatehi, S. Nowroozizadeh, Sharon Henry, A. Coleman, J. Caprioli, K. Nouri-Mahdavi   +5 more
semanticscholar   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

The contrast sensitivity of retinal ganglion cells of the cat

Journal of Physiology, 1966
C. Enroth-Cugell, J. Robson
semanticscholar   +1 more source

Monodisperse versus polydisperse ultrasound contrast agents: nonlinear\n response, sensitivity, and deep tissue imaging potential [PDF]

, 2018
Tim Segers, Pieter Kruizinga, Maarten Kok, Guillaume Lajoinie, Nico de Jong, Michel Versluis   +5 more
openalex   +1 more source

Determine Sensitivity of Diffusion Weighted Imaging for Diagnosis of Hepatocellular Carcinoma, Keeping the Liver Dynamic Post Contrast MRI as Gold Standard [PDF]

, 2022
Raana Kanwal
openalex   +1 more source