Results 131 to 140 of about 7,979,651 (342)

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Erratum to “Effect of laser peripheral iridotomy on contrast sensitivity using Spaeth/Richman Contrast Sensitivity test”

Therapeutic Advances in Ophthalmology, 2023
doaj   +1 more source

Visual contrast sensitivity could be an early marker of diabetic retinopathy [PDF]

, 2020
Subhasish Pramanik, Subhankar Chowdhury, Upasana Ganguly, Anindita Banerjee, Basudev Bhattacharya, Lakshmi Kanta Mondal   +5 more
openalex   +1 more source

Comparison of Clinical Results, Contrast Sensitivity and Optical Quality Following the Implantation of CT LUCIA 611P and TECNIS-1 ZCB00 MonofocalIOLs -12 Month Outcomes [PDF]

, 2022
Sheetal Brar, Sri Ganesh, Smith Snehal Sute, Swati Chidre   +3 more
openalex   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Correlation of visual acuity and contrast sensitivity in visually disabled patients of moderate to severe diabetic retinopathy

, 2018
M. K. Singh, V. P. Singh, P. Bhushan, RP Maurya, Pradyumn Chaturvedi   +4 more
openalex   +2 more sources

Relation of contrast sensitivity with binocularity, eye dominance and interpupillary distance in healthy adults

, 2022
Belkis Koctekin, Doğan Durmaz
openalex   +2 more sources

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

The contrast sensitivity function of a small cryptobenthic marine fish

, 2019
Matteo Santon, Thomas A. Münch, Nico K. Michiels   +2 more
openalex   +1 more source

Intersession Repeatability of Contrast Sensitivity Scores in Age-Related Macular Degeneration [PDF]

, 2009
Praveen J. Patel, Fred K. Chen, Gary S. Rubin, Adnan Tufail   +3 more
openalex   +1 more source