Results 131 to 140 of about 6,621,534 (346)
Distance and Near Visual Acuity, Contrast Sensitivity, and Visual Fields of 10-Year-Old Children [PDF]
Victoria S. Myers
openalex +1 more source
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed+8 more
wiley +1 more source
Sensibilidade ao contraste a grades senoidais de freqüências espaciais baixas em crianças
O objetivo deste trabalho foi determinar a função de sensibilidade ao contraste para freqüências espaciais de 0,25; 0,5; 1,0 e 2,0 ciclos por grau em crianças de 4 a 13 anos.
Natanael Antonio dos Santos+1 more
doaj +1 more source
Are Contrast Sensitivity Functions Impaired in Insulin Dependent Diabetics Without Diabetic Retinopathy? [PDF]
Vladimír Liška, Miroslav Dostálek
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Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho+11 more
wiley +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source
Influence of pattern height on the visual contrast sensitivity for vertical grating patterns
Yoshimichi Ejima+3 more
openalex +2 more sources
Enhancement of BOLD-contrast sensitivity by single-shot multi-echo functional MR imaging [PDF]
Stefan Posse+9 more
openalex +1 more source
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau+9 more
wiley +1 more source