Results 91 to 100 of about 2,583,441 (289)

Finding the Pill on the Floor: How Contrast Sensitivity Affects Daily Living Skills in Alzheimer’s Disease Patients [PDF]

, 2010
Alzheimer’s disease (AD) is a progressive brain disorder that gradually destroys an individual’s mental functioning and social capabilities, including the ability to carry out everyday activities.
Colon, Marlyn
core   +1 more source

Improving visual functions in adult amblyopia with combined perceptual training and transcranial random noise stimulation (tRNS): a pilot study [PDF]

, 2014
Amblyopia is a visual disorder due to an abnormal pattern of functional connectivity of the visual cortex and characterized by several visual deficits of spatial vision including impairments of visual acuity (VA) and of the contrast sensitivity function (
Astle, Astle, Astle, Bach, Berardi, Brainard, Camilleri, Chung, Chung, Ciuffreda, Epelbaum, Fertonani, Fiorentini, Greenwald, Huang, Karni, Levi, Levi, Levi, Levi, Levi, Levitt, Li, Li, Li, Loudon, McKee, Pelli, Pirulli, Poggio, Polat, Polat, Polat, Polat, Poreisz, Pourtois, Robaei, Sagi, Schoups, Schoups, Wallace, Zhou   +41 more
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Differential sensitivity of brainstem vs cortical astrocytes to changes in pH reveals functional regional specialization of astroglia [PDF]

, 2013
Astrocytes might function as brain interoceptors capable of detecting different (chemo)sensory modalities and transmitting sensory information to the relevant neural networks controlling vital functions.
Castaldo, C, Gourine, A, Kasimov, V, Kasparov, Sergey, Larina, O, Marina, N, Patrushev, M   +6 more
core   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Combined influence of illness duration and medication type on visual sensitivity in schizophrenia

Brazilian Journal of Psychiatry
Objective: Patients with schizophrenia have visual processing impairments. The main findings from the literature indicate that these deficits may be related to differences in paradigms, medications, and illness duration.
Natalia L. Almeida, Thiago P. Fernandes, Eveline H. Lima, Hemerson F. Sales, Natanael A. Santos   +4 more
doaj   +1 more source

Rectifying calibration error of Goldmann applanation tonometer is easy!

Indian Journal of Ophthalmology, 2014
Purpose: Goldmann applanation tonometer (GAT) is the current Gold standard tonometer. However, its calibration error is common and can go unnoticed in clinics. Its company repair has limitations.
Nikhil S Choudhari, Krishna P Moorthy, Vinod B Tungikar, Mohan Kumar, Ronnie George, Harsha L Rao, Sirisha Senthil, Lingam Vijaya, Chandra Sekhar Garudadri   +8 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Diurnal variation in central corneal thickness and intraocular pressure in eyes with pseudoexfoliation syndrome without glaucoma

Indian Journal of Ophthalmology, 2014
Aim: The aim was to ascertain if any differences exist in diurnal central corneal thickness (CCT) and intra-ocular pressure (IOP) between eyes with pseudoexfoliation (PXF) syndrome without glaucoma and eyes with no ocular pathology.
Stuart Keel, Linda Malesic, Siew-Pang Chan   +2 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source