Results 81 to 90 of about 2,583,441 (289)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Preoperative corneal astigmatism among adult patients with cataract in Northern Nigeria
Indian Journal of Ophthalmology, 2014 The prevalence and nature of corneal astigmatism among patients with cataract has not been well-documented in the resident African population. This retrospective study was undertaken to investigate preexisting corneal astigmatism in adult patients with ...
Mohammed Isyaku +2 more
doaj +1 more source
Fingerprints of Majorana bound states in Aharonov Bohm geometry
, 2016 We study a ring geometry, coupled to two normal metallic leads, which has a Majorana bound state (MBS) embedded in one of its arm and is threaded by Aharonov Bohm ($\mathcal{A}\mathcal{B}$) flux $\phi$.
Das, Sourin +2 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Clinical Ophthalmology, 2018 Donald R Nixon, Nicholas AP Flinn Trimed Eye Center, Barrie, ON, Canada Purpose: This study aims to investigate changes in contrast sensitivity (CS), visual acuity (VA), central retinal thickness (CRT), and vision-related quality of life in subjects ...
Nixon DR, Flinn NAP
doaj
Impact of Dry Eye on Visual Acuity and Contrast Sensitivity: Dry Eye Assessment and Management Study. [PDF]
, 2019 SIGNIFICANCE:Identification of the association of specific signs of dry eye disease with specific visual function deficits may allow for more targeted approaches to treatment.
Asbell, Penny A +7 more
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Image saliency detection in wavelet domain based on the contrast sensitivity function
Tongxin xuebao, 2015 A method of high definition saliency detection based on contrast sensitive function and wavelet analysis was proposed in order to improve the resolution of saliency maps.Original image was filtered by contrast sensitive function in YCbCr space,which ...
Ying-chun GUO +3 more
doaj +2 more sources
Uniform apparent contrast noise: A picture of the noise of the visual contrast detection system [PDF]
A picture which is a sample of random contrast noise is generated. The noise amplitude spectrum in each region of the picture is inversely proportional to spatial frequency contrast sensitivity for that region, assuming the observer fixates the center of
Ahumada, A. J., Jr., Watson, A. B.
core +1 more source