Results 11 to 20 of about 4,886 (181)

A curated structural dataset of peptide-protein complexes reveals biases in existing datasets and principles of peptide binding. [PDF]

Protein Sci
Abstract Peptide–protein interactions are fundamental to many biological processes, and peptide design is gaining interest due to its therapeutic potential. This has led to the emergence of various structural databases, such as PepBDB and Peptipedia, that classify peptides as polypeptides with fewer than 50 amino acids. These databases provide valuable
Hamdani R, Delgado J, Serrano L.
europepmc   +2 more sources

Decoding the Heterogeneity of Diffuse Large B-Cell Lymphomas: A Comprehensive Genetic, Transcriptomic, and Phenotypic Profiling of B-Cell Lymphoma Cell Lines. [PDF]

Hematol Oncol
ABSTRACT Diffuse large B‐cell lymphoma (DLBCL) is the most prevalent form of non‐Hodgkin lymphoma, exhibiting significant molecular and clinical heterogeneity. Advances in classification integrating phenotypic, genetic, and transcriptomic features have improved diagnosis and prognosis.
Pérez-Aguilera M, Pedrosa L, Gómez S, Salazar-Ortego S, Fernández-Miranda I, Muñoz-Viana R, Martín-Acosta P, Martín-Lunas BL, Jimeno R, Yanguas-Casás N, Horcajo B, Roncador G, Martínez-Climent JA, Ortega-Molina A, Sánchez-Beato M.   +14 more
europepmc   +2 more sources

Bovine Colostrum-Derived Extracellular Vesicles Impair Cancer Cell Proliferation Through Transcriptional Dysregulation. [PDF]

J Extracell Vesicles
ABSTRACT Milk‐derived extracellular vesicles (EVs) are a promising source of molecules with therapeutic potential. Bovine colostrum is particularly enriched in EVs, which carry cargo of proteins involved in immune regulation, development and cellular signalling.
Huesa-Carballo CB, Puga B, Bravo S, Rodríguez-Pérez M, Domínguez-Novoa Y, Iglesias-García J, Hermida B, Raña I, Antelo MT, López-López R, Abal M, Barbazán J.   +11 more
europepmc   +2 more sources

Changes in serum β-synuclein precede blood biomarkers of Alzheimer pathology in Down syndrome. [PDF]

Alzheimers Dement
Abstract INTRODUCTION There is a need for early, objective markers of Alzheimer's disease (AD)‐related synapse dysfunction in adults with Down syndrome (DS). The presynaptic protein β‐synuclein is elevated in the blood of adults with DS. This study evaluates the positioning of these changes relative to changes in pathophysiological blood biomarkers ...
Cervantes González A, Morcillo-Nieto AO, Serrano S, Benejam B, Videla L, Barroeta I, Fernández S, Del Hoyo Soriano L, Hernandez AS, Maure-Blesa L, Vaqué-Alcázar L, Arranz J, Rodríguez-Baz Í, Aranha MR, Perlaza D, Lidón L, Alcolea D, Bejanin A, Carmona-Iragui M, Fortea J, Lleó A, Otto M, Oeckl P, Belbin O.   +23 more
europepmc   +2 more sources

Eating Behavior Latent Profiles and Their Associations With Body Composition in Early Childhood: The CORALS Cohort. [PDF]

Obesity (Silver Spring)
ABSTRACT Objective This study aimed to identify sex‐specific eating behavior profiles and assess the associations between eating behaviors subscales and profiles and body composition indices in Spanish preschoolers from the CORALS cohort. Methods We conducted a cross‐sectional analysis of baseline data from 1208 children aged 3–6 years (50.1% girls ...
Jimeno-Martínez A, Miguel-Berges ML, Maneschy I, Gil-Campos M, Leis R, Babio N, De Miguel-Etayo P, Navas-Carretero S, Portolés O, Colomer MF, Castro-Collado C, Picáns-Leis R, Farré N, Seral-Cortés M, Martínez JA, Jurado-Castro J, Vázquez-Cobela R, Rey-Reñones C, Pastor-Villaescusa B, Llorente-Cantarero F, Pérez-Vega KA, Salas-Salvadó J, Moreno LA, Masip G, CORALS group.   +24 more
europepmc   +2 more sources

Clinical Burden of Symptomatic HEV-3 Infection in Southern Spain. [PDF]

Aliment Pharmacol Ther
Clinical burden of symptomatic HEV‐3 infection in southern Spain. Between 2022 and 2025, 1124 patients with acute hepatitis, defined as ALT ≥ 3 times the upper limit of normal and negative screening for HAV, HBV, HCV, EBV and CMV, were evaluated in Andalusia.
Casares-Jimenez M, Ferreira-Tata C, Viciana I, Freyre-Carrillo C, Lopez-Lopez P, Perez AB, Becerril-Carral B, Fuentes A, Macías J, Rios-Muñoz L, de Luna FF, Cabezas-Fernandez MT, Corona-Mata D, Rivero-Juarez A, Rivero A.   +14 more
europepmc   +2 more sources

CONTRATO INTERMITENTE

Revista Direitos Sociais e Políticas Públicas (UNIFAFIBE), 2022
O trabalho intermitente é gênero que precisa ser dividido em duas espécies, uma com e outra sem vínculo empregatício, sob pena de retirar a eficácia dos direitos fundamentais, por falta de instrumentalidade, pois dependem da legislação trabalhista para gerarem efeitos.
Juliana Marteli Fais Feriato, Daniel Amud Zuin   +1 more
openaire   +1 more source

Estudio de los factores críticos para el éxito en la construcción de edificaciones en la ciudad de Santo Domingo, República Dominicana al año 2014

Ciencia y Sociedad, 2016
En la industria de la construcción se ha estudiado el éxito y cómo obtenerlo, además de las diferentes definiciones se ha llegado a la conclusión de que existen una serie de Factores Críticos que ayudan a alcanzarlo.
Camila Martínez, Samuel Morla, Nelson Peña, Richard Rosario, Carolina Slaiman, Heine Solis, Damaso Váldez, Coral Vargas   +7 more
doaj   +1 more source

Sobre la extrapolación de la literatura del inglés jurídico: la presencia de latinismos crudos en los contratos de colaboración estadounidenses [PDF]

Estudios Interlingüísticos, 2021
El presente artículo tiene por objetivo constatar la presencia de latinismos crudos en los contratos de colaboración estadounidenses con la finalidad de observar la posibilidad o imposibilidad de extrapolar la literatura existente sobre los latinismos ...
Valeria Hernández García
doaj  

NOTES ABOUT CROWDFUNDING IN BRAZILIAN LAW

Revista Eletrônica do Curso de Direito da UFSM, 2018
This purpose of this study is to analyse the discipline of several modalities of crowdfunding in Brazil through an exploratory and applied qualitative research work based in a bibliographic review and legislative analysis under the logic-deductive method.
Aline de Miranda Valverde Terra
doaj   +1 more source