Results 151 to 160 of about 2,197,790 (291)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Control and optimization of a half-car active suspension system with classical and modified PID-based controllers using metaheuristic techniques. [PDF]

Sci Rep
Aysal FE, Mengi OÖ, Güven AF, Bajaj M, Blazek V, Hunko I.   +5 more
europepmc   +1 more source

Least-cost control strategy optimization for air quality attainment of Beijing-Tianjin-Hebei region in China. [PDF]

J Environ Manage, 2019
Xing J, Zhang F, Zhou Y, Wang S, Ding D, Jang C, Zhu Y, Hao J.   +7 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Oil-Water Biphasic Metal-Organic Supramolecular Gel for Lost Circulation Control: Formulation Optimization, Gelation Mechanism, and Plugging Performance. [PDF]

Gels
Li Q, Li S, Zhang Y, Chen C, Wu X, Li M, Pan S, Peng J.   +7 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Corrigendum to “IoT application for energy poverty detection based on thermal comfort monitoring” [Heliyon 9 (1) (January 2023) Article e12943]

Heliyon, 2023
Ascensión López-Vargas, Agapito Ledezma-Espino   +1 more
doaj   +1 more source

Advanced control parameter optimization in DC motors and liquid level systems. [PDF]

Sci Rep
Ekinci S, Izci D, Almomani MH, Saleem K, Zitar RA, Smerat A, Snasel V, Ezugwu AE, Abualigah L.   +8 more
europepmc   +1 more source

An ultrasonic method for the synthesis, control and optimization of CdS/TiO₂ core-shell nanocomposites. [PDF]

RSC Adv, 2019
Alizadeh S, Fallah N, Nikazar M.
europepmc   +1 more source