Results 131 to 140 of about 1,090,202 (336)
Erratum: Control and Systems Engineering
, 2015 A. El-Osery, J. Prevost
semanticscholar +1 more source
Nonlinear control systems, design methods
, 1999 The sections in this article are: The Regulation Problem, Linear Time-Invariant Systems,Feedback Linearization, Passivity-Based Control, Control Under Model and Parameter Uncertainties, Third-Order Feedback Linearizable Systems, Conclusion ...
Webster, J.G., Loria, A., Nijmeijer, H.
core +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Systems and control in transportation engineering
Systems Science & Control Engineering, 2018 Qiankun Song, Bing Li, Huiwei Wang
doaj +1 more source
Modeling drug retention as memory effects in obese patients using fractional and augmented models
Scientific ReportsLipophilic anesthetic drugs accumulate in adipose tissue, leading to delayed release and prolonged effects, particularly in obese patients. This study proposes two novel physiologically motivated pharmacokinetic (PK) models to address these dynamics. The
Amani R. Ynineb +9 more
doaj +1 more source
A Test Bench To Study Bioinspired Control for Robot Walking
, 2011 Test bench to study robot walking within the predicted structures of biological control systems is discussed. Physical system is briefly presented with components.
Irfanoglu, Bulent, Arikan, Kutluk B.
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source