Results 121 to 130 of about 806,495 (313)

A modified CNN-IDS model for enhancing the efficacy of intrusion detection system

Measurement: Sensors
As the security of computer networks in enterprises worldwide is dependent on the proper functioning of intrusion detection systems (IDSs) and intrusion prevention systems (IPSs), this effectiveness of both of them is of utmost priority.
Ruqaya Abdulhasan Abed, Ekhlas Kadhum Hamza, Amjad J. Humaidi   +2 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Command and control for distributed lethality [PDF]

, 2017
Exercising command and control (C2) during naval distributed lethality operations presents a complex system of systems (SOS) challenge in support of maritime control. Applying a model based systems engineering (MBSE) approach to C2 within the distributed
Kelly, Erik, Jankowski, William, Watson, Scott, Smith, Sarah, Enloe, Michael, Kummer, Gerald, Kummer, Keren, Corbett, Logan   +7 more
core  

Control Engineering and Management Systems

Measurement + Control, 1969
V. A. J. Gifford DLC, CEng, MIProdE, FIWSP, MBIM
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Identification for robust control of complex systems : algorithm and motion application

, 2015
Increasing performance demands in control applications necessitate accurate modeling of complex systems for control. The aim of this chapter is to develop a new system identification algorithm that delivers models that are suitable for subsequent robust ...
Steinbuch, M., Oomen, T.A.E., Lovera, M.
core   +1 more source

Improving airport security with IoT-powered deep learning methods for threat detection and intelligent recommendation systems

Scientific Reports
This study introduces a novel framework that integrates deep learning algorithms, intelligent recommendation systems, and Internet-of-things (IoT) devices to improve airport security.
Mohamed Basem, John Zaki, M. Sabry Saraya, Fatma M. Talaat   +3 more
doaj   +1 more source

Low-Cost IoT Air Quality Monitoring Station Using Cloud Platform and Blockchain Technology

Applied Sciences
Air pollution is a growing concern due to severe threats to public health and the environment. The need for reliable air quality monitoring solutions has never been more critical.
Ahmed K. Hassan, Mohamed S. Saraya, Amr M. T. Ali-Eldin, Mohamed M. Abdelsalam   +3 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source