Results 111 to 120 of about 806,495 (313)

Accelerated optimization in deep learning with a proportional-integral-derivative controller

Nature Communications
High-performance optimization algorithms are essential in deep learning. However, understanding the behavior of optimization (i.e., learning process) remains challenging due to the instability and weak interpretability of the algorithms.
Song Chen, Jiaxu Liu, Pengkai Wang, Chao Xu, Shengze Cai, Jian Chu   +5 more
doaj   +1 more source

Temperature and Flow Decoupling Control for Air Heater Systems [PDF]

Journal of Electrical and Electronics Engineering, 2014
In this paper it is presented an optimized practical solution for controlling the temperature and flow of a multivariable process. The solution is based on software architecture that solves the technical problem of coupling between the two parameters ...
SOPONARIU Alexandru, LUPU Ciprian
doaj  

Distributed Dynamic Reference Governor for Constrained Semi-Autonomous Robotic Swarms with Communication Delays and Experimental Verification

SICE Journal of Control, Measurement, and System Integration, 2019
This paper investigates constrained semi-autonomous robotic swarms in the presence of inter-robot communication delays. The objective is that all robots converge to the optimal point related to the reference given by a human operator without violating ...
Aditya Wildan Farras, Takeshi Hatanaka, Tam W. Nguyen, Riku Funada, Junya Yamauchi, Masayuki Fujita   +5 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

A Vision of Collaborative Verification-Driven Engineering of Hybrid Systems

, 2013
Hybrid systems with both discrete and continuous dynamics are an important model for real-world physical systems. The key challenge is how to ensure their correct functioning w.r.t. safety requirements.
Stefan Mitsch, Grant Olney Passmore (5415671), Mitsch, Stefan, Platzer, André, Grant Olney Passmore, Andre Platzer (5363771), Passmore, Grant Olney, Stefan Mitsch (5415674), André Platzer   +8 more
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Nonlinear control systems, design methods

, 1999
The sections in this article are: The Regulation Problem, Linear Time-Invariant Systems,Feedback Linearization, Passivity-Based Control, Control Under Model and Parameter Uncertainties, Third-Order Feedback Linearizable Systems, Conclusion ...
Webster, J.G., Loria, A., Nijmeijer, H.
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

A combined feedforward-feedback controller design for nonlinear systems

Open Engineering
This study presents a control framework that integrates both feedforward (FF) and feedback (FB) procedures to control nonlinear systems. The intelligent control component consisted of a modified recurrent wavelet neural network used to build the FF ...
Abdulkareem Jenan J., Ali Hazem I., Lutfy Omar Farouq   +2 more
doaj   +1 more source