Results 111 to 120 of about 1,090,202 (336)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Accelerated optimization in deep learning with a proportional-integral-derivative controller

open access: yesNature Communications
High-performance optimization algorithms are essential in deep learning. However, understanding the behavior of optimization (i.e., learning process) remains challenging due to the instability and weak interpretability of the algorithms.
Song Chen   +5 more
doaj   +1 more source

Temperature and Flow Decoupling Control for Air Heater Systems [PDF]

open access: yesJournal of Electrical and Electronics Engineering, 2014
In this paper it is presented an optimized practical solution for controlling the temperature and flow of a multivariable process. The solution is based on software architecture that solves the technical problem of coupling between the two parameters ...
SOPONARIU Alexandru, LUPU Ciprian
doaj  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Engineering vibration analysis with application to control systems /

open access: yes, 1996
Most machines and structures are required to operate with low levels of vibration as smooth running leads to reduced stresses and fatigue and little noise.
Beards, C. F.
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Digital Control Systems Implementation Techniques

open access: yes, 1995
Praise for Previous Volumes "This book will be a useful reference to control engineers and researchers. The papers contained cover well the recent advances in the field of modern control theory."--IEEE GROUP CORRESPONDANCE "This book will help all those ...
Leondes, Cornelius T.   +1 more
core  

Control of Mechatronic Systems

open access: yes, 2017
This book introduces researchers and advanced students with a basic control systems background to an array of control techniques which they can easily implement and use to meet the required performance specifications for their mechatronic applications ...
Bilin Aksun-Güvenç   +7 more
core   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

A combined feedforward-feedback controller design for nonlinear systems

open access: yesOpen Engineering
This study presents a control framework that integrates both feedforward (FF) and feedback (FB) procedures to control nonlinear systems. The intelligent control component consisted of a modified recurrent wavelet neural network used to build the FF ...
Abdulkareem Jenan J.   +2 more
doaj   +1 more source

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