Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Engineering vibration analysis with application to control systems /
, 1996 Most machines and structures are required to operate with low levels of vibration as smooth running leads to reduced stresses and fatigue and little noise.
Beards, C. F.
core
Automatic tuning and adaptation for PID controllers - a survey
, 1992 Control Engineering Practice14699 ...
Åström, K.J. +14 more
core +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Accelerated optimization in deep learning with a proportional-integral-derivative controller
Nature CommunicationsHigh-performance optimization algorithms are essential in deep learning. However, understanding the behavior of optimization (i.e., learning process) remains challenging due to the instability and weak interpretability of the algorithms.
Song Chen +5 more
doaj +1 more source
A Test Bench To Study Bioinspired Control for Robot Walking
, 2011 Test bench to study robot walking within the predicted structures of biological control systems is discussed. Physical system is briefly presented with components.
Irfanoglu, Bulent, Arikan, Kutluk B.
core
Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease
FEBS Letters, EarlyView.Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim +4 more
wiley +1 more source
A combined feedforward-feedback controller design for nonlinear systems
Open EngineeringThis study presents a control framework that integrates both feedforward (FF) and feedback (FB) procedures to control nonlinear systems. The intelligent control component consisted of a modified recurrent wavelet neural network used to build the FF ...
Abdulkareem Jenan J. +2 more
doaj +1 more source