Results 71 to 80 of about 1,090,202 (336)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Design of Nonlinear PID and FOPID Controllers for Electronic Throttle Valve Plate’s Position

Journal of Electrical and Computer Engineering
The electronic throttle valve (ETV) system is one of the essential parts of the automobile because it controls the amount of airflow into the engine’s combustion system. In fact, there are challenges in ETV control due to several nonsmooth nonlinearities,
Mohamed Jasim Mohamed, Luay Thamir Rasheed   +1 more
doaj   +1 more source

Critical damping characteristics of a SDOF system with fractional derivative of a wide range of order

Nihon Kikai Gakkai ronbunshu, 2018
In this study, vibration characteristics of a single-degree-of-freedom linear oscillator with the fractional order derivative are examined in terms of the critical damping over a wide range of the order of the fractional derivative by using numerical ...
Hideyuki KIMURA, Takahiro TSUCHIDA, Koji KIMURA   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Optimal control of hybrid vehicles

, 2013
Optimal Control of Hybrid Vehicles provides a description of power train control for hybrid vehicles. The background, environmental motivation and control challenges associated with hybrid vehicles are introduced.
Jager, Bram, Jager, de, A.G., Keulen, van, T.A.C., Keulen, Thijs, Kessels, John, Kessels, J.T.B.A.   +5 more
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

A proposed plant classification framework for smart agricultural applications using UAV images and artificial intelligence techniques

Alexandria Engineering Journal
Utilizing Wireless Sensor Networks (WSNs), Internet of Things (IoTs) sensors, and Unmanned Aerial Vehicles (UAVs), in conjunction with optimization techniques and machine learning algorithms, can present a novel approach to Precision Agricultural (PA ...
Shymaa G. Eladl, Amira Y. Haikal, Mahmoud M. Saafan, Hanaa Y. ZainEldin   +3 more
doaj   +1 more source

An Advanced Helicopter Engine Control System [PDF]

Aircraft Engineering and Aerospace Technology, 1982
The Amalgamation of Functions The requirements of the first engine controllers were primarily to satisfy the needs of the engine and, almost as an afterthought, to consider interface with the aircraft and the pilot. The latter resulted in the overwhelming plethora of “essential” ground test‐sets and cockpit instruments that we see today.
openaire   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source