Results 61 to 70 of about 3,372,464 (292)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

A Product Line Systems Engineering Process for Variability Identification and Reduction

, 2018
Software Product Line Engineering has attracted attention in the last two decades due to its promising capabilities to reduce costs and time to market through reuse of requirements and components.
Dickerson, Charles, Grigg, Alan, Guan, Lin, Ji, Siyuan, Li, Mole   +4 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Design of Nonlinear PID and FOPID Controllers for Electronic Throttle Valve Plate’s Position

Journal of Electrical and Computer Engineering
The electronic throttle valve (ETV) system is one of the essential parts of the automobile because it controls the amount of airflow into the engine’s combustion system. In fact, there are challenges in ETV control due to several nonsmooth nonlinearities,
Mohamed Jasim Mohamed, Luay Thamir Rasheed   +1 more
doaj   +1 more source

A proposed plant classification framework for smart agricultural applications using UAV images and artificial intelligence techniques

Alexandria Engineering Journal
Utilizing Wireless Sensor Networks (WSNs), Internet of Things (IoTs) sensors, and Unmanned Aerial Vehicles (UAVs), in conjunction with optimization techniques and machine learning algorithms, can present a novel approach to Precision Agricultural (PA ...
Shymaa G. Eladl, Amira Y. Haikal, Mahmoud M. Saafan, Hanaa Y. ZainEldin   +3 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Critical damping characteristics of a SDOF system with fractional derivative of a wide range of order

Nihon Kikai Gakkai ronbunshu, 2018
In this study, vibration characteristics of a single-degree-of-freedom linear oscillator with the fractional order derivative are examined in terms of the critical damping over a wide range of the order of the fractional derivative by using numerical ...
Hideyuki KIMURA, Takahiro TSUCHIDA, Koji KIMURA   +2 more
doaj   +1 more source

LQR/Sliding Mode Controller Design Using Particle Swarm Optimization for Crane System

مجلة النهرين للعلوم الهندسية, 2020
In this work, the design procedure of a hybrid robust controller for crane system is presented. The proposed hybrid controller combines the linear quadratic regulator (LQR) properties with the sliding mode control (SMC) to obtain an optimal and robust ...
Hazem Ali, Azhar Jabbar Abdulridha, Rawaa Khaleel, Kareem Kareem A. Hussein   +3 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source