Results 81 to 90 of about 3,372,464 (292)

Ethical and Social Aspects of Self-Driving Cars

, 2018
As an envisaged future of transportation, self-driving cars are being discussed from various perspectives, including social, economical, engineering, computer science, design, and ethics.
Dodig-Crnkovic, Gordana, Holstein, Tobias, Pelliccione, Patrizio   +2 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Pose Synchronization for Quadrotor Networks under Fixed General Interconnection Topology: A Passivity Approach

SICE Journal of Control, Measurement, and System Integration, 2018
In this paper, a distributed 3-D pose synchronization law is proposed for a group of networked quadrotors. The quadrotor network consisting of multiple quadrotors with dynamics and interconnection topology between them is first defined, and then, the ...
Tatsuya Ibuki, Satoshi Nakano, Mahato Endou, Mitsuji Sampei   +3 more
doaj   +1 more source

Design Space Exploration in Cyber-Physical Systems [PDF]

, 2019
Cyber physical systems (CPS) integrate a variety of engineering areas such as control, mechanical and computer engineering in a holistic design effort.
Amir, Maral
core  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Back stepping-Based-PID-Controller Designed for an Artificial Pancreas model

Al-Khawarizmi Engineering Journal, 2011
Artificial pancreas is simulated to handle Type I diabetic patients under intensive care by automatically controlling the insulin infusion rate. A Backstepping technique is used to apply the effect of PID controller to blood glucose level since there is ...
Taghreed M. Mohammad Ridha, Mina Qais Kadhum, Shaima Mahmou Mahdi   +2 more
doaj  

DMARS_WGO: a deep reinforcement-driven hybrid metaheuristic for intelligent adaptive optimization

Scientific Reports
Metaheuristics optimization algorithms have established themselves as a new cornerstone in the area of complex, nonlinear, and high-dimensional problems of science and engineering.
Nada R. Yousif, Eman M. El-Gendy, Amira Y. Haikal   +2 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

MSCADMpox: A novel multi-stage classification model for effective monkeypox classification

Complex & Intelligent Systems
Monkeypox (Mpox) is a skin disease that appeared after the COVID-19 pandemic and spread to 127 countries. Early diagnosis of Mpox according to symptoms is difficult because it is closer to measles and chickenpox symptoms, while both lesions are ...
Doaa Ahmed Arafa, Sarah M. Ayyad, Mohamed M. Abdelsalam   +2 more
doaj   +1 more source

Achieving Ultra-Low Latency in 5G Millimeter Wave Cellular Networks

, 2016
The IMT 2020 requirements of 20 Gbps peak data rate and 1 millisecond latency present significant engineering challenges for the design of 5G cellular systems.
Dutta, Sourjya, Ford, Russell, Mezzavilla, Marco, Rangan, Sundeep, Zhang, Menglei, Zorzi, Michele   +5 more
core   +1 more source