Results 41 to 50 of about 102,544 (278)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

High throughput mechanical property testing of materials libraries using a piezoelectric [PDF]

, 2003
The present invention provides instruments and methods for screening combinatorial libraries that addresses many of the problems encountered when using conventional instruments.
Carlson, Eric D., Carlson, Eric, Shrinivasan, Ravi, Safir, Adam, Hajduk, Damian, Freitag, Christopher, Engstrom, James, Kolosov, Oleg, Matsiev, L, Hajduk, Damian A.   +9 more
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Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Potential applications of artificial intelligence in spent nuclear fuel reprocessing research: A review

Nuclear Engineering and Technology
Spent nuclear fuel reprocessing plays a pivotal role in achieving a closed nuclear fuel cycle. However, traditional research approaches face significant obstacles due to the highly radioactive environment, limited availability of experimental data, and ...
Tianchi Li, Qi Chen, Jia Zhou, Yandong Sun, Yanhong Jia, Yang Bai, Jianhua Guo, Qiuyue Zhang, Xiaojin Wang, Fangliang Yao, Zhi Cao, Wentao Wang, Fang Liu, Taihong Yan, Weifang Zheng   +14 more
doaj   +1 more source

The Synthesis of Anatase Nanoparticles and the Preparation of Photocatalytically Active Coatings Based on Wet Chemical Methods for Self-Cleaning Applications

International Journal of Photoenergy, 2012
We report on an improved sol-gel method for the production of highly photocatalytic titanium dioxide (TiO2) anatase nanoparticles which can provide appropriate control over the final characteristics of the nanoparticles, such as particle size ...
Dejan Verhovšek, Nika Veronovski, Urška Lavrencic Štangar, Marko Kete, Kristina Žagar, Miran Ceh   +5 more
doaj   +1 more source

Translation of bone wax and its substitutes: History, clinical status and future directions

Journal of Orthopaedic Translation, 2019
Bone wax, primarily composed of beeswax and softening agent, is a century-old material used to control bleeding of disrupted bone surfaces by acting as a mechanical barrier to seal the wound.
Huan Zhou, Jun Ge, Yanjie Bai, Chunyong Liang, Lei Yang   +4 more
doaj   +1 more source

Operational comparison of two types of tractor sprayers (microner and boom-type) against wheat crop weeds [PDF]

Journal of Agricultural Machinery, 2015
Introduction: Nowadays, the tractor mounted boom sprayer is used in many agricultural fields. These sprayers have many advantages compared to other sprayers, but in Iran, their field efficiency is much lower than that of the developed countries, because ...
M Hamid, H Zaki Dizaji, A Marzban
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Studies into the Failure Prediction of Brittle Materials [PDF]

, 1987
This thesis is divided into six chapters. The first chapter provides a brief introduction concerning the behaviour of brittle materials. It also contains the justification for the undertaking of the study as well as a brief description of the method ...
Nguyen, P. D.
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