Results 51 to 60 of about 102,544 (278)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Production, handling and characterization of particulate materials

open access: yes, 2016
This edited volume presents most techniques and methods that have been developed by material scientists, chemists, chemical engineers and physicists for the commercial production of particulate materials, ranging from the millimeter to the nanometer ...
Merkus, Henk, Meesters, Gabriel
core   +1 more source

A Critical Review of Risk Assessment and Control Strategies for Ammonia Storage and Handling in Maritime Decarbonisation

open access: yesJournal of Marine Science and Engineering
Ammonia is a promising zero-carbon energy carrier for maritime decarbonisation, but its deployment is limited by safety risks that are not adequately addressed by conventional marine fuel safety frameworks. This study critically reviews safety assessment,
Zahra Barbari   +5 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Field Data Acquisition Technologies for Iowa Transportation Agencies, HR-366 August 1994 [PDF]

open access: yes, 1994
This report describes the results of the research project investigating the use of advanced field data acquisition technologies for lowa transponation agencies.

core  

A microgripper based on electrothermal Al–SiO2 bimorphs

open access: yesMicrosystems & Nanoengineering
Microgrippers are essential for assembly and manipulation at the micro- and nano-scales, facilitating important applications in microelectronics, MEMS, and biomedical engineering.
Hengzhang Yang   +9 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

An expert system for material handling equipment selection [PDF]

open access: yes
Manufacturing Systems are subject to increasingly frequent changes in demand in terms of number and type of products they produce. It is impractical to continually reconfigure the facilities, but it is possible to modify the material handling ...
Al-Meshaiei, Eisa Abdullah Eisa S.
core  

Robotic control architecture development for automated nuclear material handling systems [PDF]

open access: yes, 1995
Lawrence Livermore National Laboratory (LLNL) is engaged in developing automated systems for handling materials for mixed waste treatment, nuclear pyrochemical processing, and weapon components disassembly.
Merrill, R.D.   +3 more
core  

Costing oral cholera vaccine delivery using a generic oral cholera vaccine delivery planning and costing tool (CholTool)

open access: yesHuman Vaccines & Immunotherapeutics, 2020
Cholera is both an endemic and epidemic disease in many low and middle-income countries (LMICs). Strategies for cholera control include improving water, sanitation, and hygiene; providing early and effective treatment; and deploying oral cholera vaccine (
Winthrop Morgan   +3 more
doaj   +1 more source

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