Results 71 to 80 of about 102,544 (278)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Materials selection for microsystems actuators

, 2008
The recent developments of novel thin film materials and their associated processes have marked the onset of change in the design philosophy of Micro-Electro- Mechanical Systems (MEMS) from process centric to performance centric.
Srinivasan, Prasanna
core  

In Vivo Evaluation of Demineralized Bone Matrix with Cancellous Bone Putty Formed Using Hydroxyethyl Cellulose as an Allograft Material in a Canine Tibial Defect Model

Animals
Demineralized bone matrix (DBM) is a widely used allograft material for bone repair, but its handling properties and retention at defect sites can be challenging.
Donghyeok Yoo, Minha Oh, Minkyung Kim, Dongbin Lee   +3 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Sensing and Control within a Robotic End Effector

, 1997
This research programme investigates aspects of end effector design and control, to carry out grasping operations in a range of unstructured environments. A conceptual three fingered end effector design has been developed.
Dubey, Venketeshwar Nath
core  

Autonomous materials handling robot for reconfigurable manufacturing systems. [PDF]

, 2010
Thesis (M.Sc.Eng.)-University of KwaZulu-Natal, Durban, 2010.The concept of mass producing custom products, though extremely beneficial to the commercial, and retail industries, does come with some limitations.
Butler, Louwrens Johannes.
core  

Effects on logistic operations from RFID- and EPCIS-enabled traceability [PDF]

, 2014
Purpose – The paper aims to explore the potential effects on logistic operations of implementing the Electronic Product Code Information Service (EPCIS) standard and radio frequency identification (RFID) technology to enable food traceability.
Ringsberg, Henrik, Mirza Beiki, Vahid,, Mirza Beiki, Vahid, Ringsberg, Henrik,, Ringsberg, Henrik Anders, Mirzabeiki, Vahid   +5 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Autonomous Material Handling Systems in Smart Factories: Advanced Path Planning and Control of Industrial Robots for Manufacturing Applications

International Journal of Research
The evolution of smart factories within Industry 4.0 is fundamentally dependent on the seamless and intelligent movement of materials. Autonomous Material Handling Systems, particularly those employing advanced industrial robots, have transitioned from fixed automation to flexible, intelligent agents central to cyber-physical production systems.
openaire   +2 more sources

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source