Results 61 to 70 of about 102,544 (278)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Imaging Techniques Applied to Bulk Handling and Processing

open access: yes, 1997
The emerging interest in these last few years on the adoption of techniques for the image analysis to detect information on static or moving objects has enabled the adoption of these procedures possible also in industrial and research sectors which are ...
BONIFAZI, Giuseppe
core  

Multibody Analysis of Sloshing Effect in a Glass Cylinder Container for Visual Inspection Activities

open access: yesApplied Sciences
This paper addresses the phenomenon of sloshing and the issues that arise during liquid handling at visual inspection stations. The pharmaceutical industry, recently put under pressure by the pandemic, has long adopted modular solutions consisting mainly
Marco Claudio De Simone   +3 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Decison support system for pallet utilisation in the sheet feeder industry [PDF]

open access: yes, 2008
This thesis aims at developing a decision support system for pallet utilisation in the sheet feeder industry. Furthermore, the research project has focused on providing an improvement to the current system of distribution of the customer order onto ...
Celaya Lejarza, Olatz
core  

Photoelasticity based dynamic tactile sensor [PDF]

open access: yes, 2005
The paper presents design, construction and testing of a photoelasticity based dynamic sensor which is capable of detecting slip as well as providing normal force information.
Richard M. Crowder   +5 more
core   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Computer simulation applied to parcel conveyors

open access: yes, 1979
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The research reported by this thesis concerns the operation of Post Office parcel conveyors.
Rourke, JW
core  

Challenges and Innovations in Liquefied Gases and Cryogenic Tanks: A Comprehensive Review

open access: yesTechnologies
Cryogenic technologies are a crucial field of modern engineering, with applications in liquefied gas transport, renewable energy, aerospace, and high-precision medicine.
Marian-Cristian Staicu   +3 more
doaj   +1 more source

Decrease in Consumption of Compressed Air in Dry Ice Blasting Machine

open access: yesChemical Engineering Transactions, 2014
Dry ice blasting is a highly efficient and environmental friendly method for elimination of undesired layers from various materials. Dry ice blasting is used especially in cleaning of industrial manufacturing moulds, welding robots, and many other ...
V. Máša   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy