Results 51 to 60 of about 2,353,723 (293)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Nonlinear H ∞ optimal control scheme for an underwater vehicle with regional function formulation [PDF]
, 2013 A conventional region control technique cannot meet the demands for an accurate tracking performance in view of its inability to accommodate highly nonlinear system dynamics, imprecise hydrodynamic coefficients, and external disturbances.
Dunnigan, Mathew Walter, Ismail, Zool
core +2 more sources
Robust Control for the Segway with Unknown Control Coefficient and Model Uncertainties [PDF]
Sensors, 2016 The Segway, which is a popular vehicle nowadays, is an uncertain nonlinear system and has an unknown time-varying control coefficient. Thus, we should consider the unknown time-varying control coefficient and model uncertainties to design the controller.
Kim, Byung Woo, Park, Bong Seok
openaire +4 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Development of a theoretical model for upright postural control in lower limb prosthesis users
Scientific Reports, 2021 Methods used to assess quiet standing in unilateral prosthesis users often assume validity of an inverted pendulum model despite this being shown as invalid in some instances.
David F. Rusaw +5 more
doaj +1 more source
Controller System Design Using the Coefficient Diagram Method
Arabian Journal for Science and Engineering, 2016 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Coelho, João Paulo +2 more
openaire +2 more sources
Metabolic control analysis [PDF]
European Journal of Biochemistry, 1990 This paper illustrates a method to calculate the sensitivities of control coefficients to the elasticities which determine their values and it is shown that these sensitivities are systemic properties. We show, both theoretically and with a practical example, how they can be used to investigate: (a) the relative importance of a particular elasticity in
J R, Small, D A, Fell
openaire +2 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
, 2016 This paper brings out results of a measurement campaign aiming to determine the temperature coefficients of synthetic quartz elastic constants at liquid helium temperature.
Bon, Jérémy +2 more
core +3 more sources